September 26, 2024 by University of Geneva Immunofluorescence staining of a representative human glioblastoma tissue section. In red, the PTPRZ1 markers, and in blue, the cell nuclei. (scale bar: 400 μm). Credit: Denis Migliorini – UNIGE/HUGScientists at UNIGE and HUG have developed CAR-T cells capable of targeting malignant gliomas while preserving healthy tissue. Glioblastoma is...
Tag: <span>CAR-T cells</span>
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Boosting CAR-T cell therapies from under the skin
NEWS RELEASE 12-JUN-2024 Subcutaneous biodegradable scaffolds for restimulating the antitumor activity of preadministered CAR-T cells Peer-Reviewed PublicationWYSS INSTITUTE FOR BIOLOGICALLY INSPIRED ENGINEERING AT HARVARD IMAGE: T-CELL ENHANCING SCAFFOLDS CAN BE LOCALLY INJECTED UNDER THE SKIN FOLLOWING CAR-T CELL THERAPY, AND ALLOWCIRCULATING CAR-T CELLS TO INFILTRATE THEIR 3-DIMENSIONAL POROUS SCAFFOLD STRUCTURE. THERE, CAR-T CELLS BECOME ACTIVATED...