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Cardiomyocytes study discovers new way to regenerate damaged heart cells
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Cardiomyocytes study discovers new way to regenerate damaged heart cells

MAY 31, 2024 by Olivia Dimmer, Northwestern University Credit: Unsplash/CC0 Public Domain Northwestern Medicine scientists have discovered a way to regenerate damaged heart muscle cells in mice, a development that may provide a new avenue for treating congenital heart defects in children and heart attack damage in adults, according to a study published in the...

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Direct reprogramming: Defying the contemporary limitations in cardiac regeneration

This article by Dr. Vivekanandan Palaninathan et al. is published in Current Pharmaceutical Design, 2020 BENTHAM SCIENCE PUBLISHERS Direct reprogramming or Transdifferentiation is a way of inducing changes in the cell type from one lineage into another lineage, bypassing pluripotency. This approach is an innovative choice to replace the lost cardiomyocytes after an end-stage myocardial...

Slow release of two chemicals protects the heart after experimental heart attacks
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Slow release of two chemicals protects the heart after experimental heart attacks

Injections of two chemicals in a slow-release form significantly reduced the size of dead heart tissue and improved the function of the left ventricle. UNIVERSITY OF ALABAMA AT BIRMINGHAM BIRMINGHAM, Ala. – A novel treatment reduces heart damage after serious heart attacks in two animal models. Injections of two chemicals in a slow-release form significantly...

Revealed: two men in China were first to receive pioneering stem-cell treatment for heart-disease
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Revealed: two men in China were first to receive pioneering stem-cell treatment for heart-disease

Two men in China were the first people in the world to receive an experimental treatment for heart disease based on ‘reprogrammed’ stem cells and have recovered successfully one year later, says the cardiac surgeon who performed the procedures. In May last year, the men were injected with heart muscle cells derived from induced pluripotent...

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Diseased heart muscle cells have abnormally shortened telomeres, researchers find

People with a form of heart disease called cardiomyopathy have abnormally short telomeres in heart muscle cells responsible for contraction, according to a new study by researchers at the Stanford University School of Medicine. Human chromosomes (grey) capped by telomeres (white). Credit: PD-NASA; PD-USGOV-NASA A telomere is a DNA sequence that serves as a protective cap on the ends...