by University of Eastern Finland Schematic illustration depicting miR-466c targeting of murine Vegfa promoter. Credit: PLOS ONE (2022). DOI: 10.1371/journal.pone.0265948 A novel angiogenic microRNA drug can be a new option for the treatment of ischemic cardiovascular disease, according to a new study published in PLOS One by researchers from the University of Eastern Finland together with international collaborators. In...
by American Heart Association Credit: CC0 Public Domain Eating two or more servings of avocado weekly was associated with a lower risk of cardiovascular disease, and substituting avocado for certain fat-containing foods like butter, cheese or processed meats was associated with a lower risk of cardiovascular disease events, according to new research published today in...
by University of Connecticut Credit: CC0 Public Domain Macrophages travel through our arteries, gobbling fat the way Pac-man gobbled ghosts. But fat-filled macrophages can narrow blood vessels and cause heart disease. Now, UConn Health researchers describe in Nature Cardiovascular Research how deleting a protein could prevent this and potentially prevent heart attacks and strokes in humans. Macrophages are...
by American Heart Association Credit: Unsplash/CC0 Public Domain Routine mammograms may provide key insights for cardiovascular disease. Detection of breast arterial calcifications on breast mammograms was associated with a higher risk of cardiovascular disease in postmenopausal women, according to new research published today in Circulation: Cardiovascular Imaging, a peer-reviewed journal of the American Heart Association journal....
PLOS IMAGE: STUDY DESIGN SCHEMATIC: GRAPHICAL OUTLINE OF THE COHORT STUDY TO ASSESS FUTURE TYPE 2 DIABETES AND CARDIOVASCULAR DISEASE RISK BY INTEGRATING GENETICS, LIPIDOMICS AND STANDARD CLINICAL DIAGNOSTICS. CREDIT: LIPOTYPE (CC BY 4.0, HTTPS://CREATIVECOMMONS.ORG/LICENSES/BY/4.0/) Simultaneous measurement of dozens of types of fats in the blood (“lipidomics”) can predict the risk of developing type 2 diabetes...
by Frontiers Credit: CC0 Public Domain A sufficient intake of vegetables is important for maintaining a balanced diet and avoiding a wide range of diseases. But might a diet rich in vegetables also lower the risk of cardiovascular disease (CVD)? Unfortunately, researchers from the Nuffield Department of Population Health at the University of Oxford, the...
by McMaster University A The effect of caffeine (CF; 200 µM) on SREBP2 and SREBP1 mRNA expression was examined in primary mouse hepatocytes (PMH) in the presence and absence of thapsigargin (TG; 100 nM), an established activator of SREBPs. The downstream product of SREBP2 transcriptional activity, HMGR, was also examined. B, C The inhibitory effect of CF...
PLOS IMAGE: SU/ ÖSTRA: INSIDE BY NIGHT CREDIT: MESCON, FLICKR (CC BY 2.0, HTTPS://CREATIVECOMMONS.ORG/LICENSES/BY/2.0/) Among patients with chronic, non-communicable diseases, the risk of death is more than doubled if they also have a psychiatric comorbidity, according to a new study publishing January 27th in PLOS Medicine by Seena Fazel of the University of Oxford, UK, and colleagues. Non-communicable diseases...
by Karolinska Institutet Credit: Unsplash/CC0 Public Domain The risk of developing cardiovascular disease is strongly associated with the “bad” LDL cholesterol. A large study by scientists at Karolinska Institutet now shows that two proteins that transport cholesterol particles in the blood provide early and reliable risk information. The researchers now advocate introducing new guidelines for detecting...
by Julia Evangelou Strait, Washington University School of Medicine A cross section of a peripheral artery from the leg of a patient with chronic limb-threatening ischemia, a condition in which heavy plaque formation causes a severe narrowing of the arteries. A new study from Washington University School of Medicine in St. Louis has identified a key...
