by University of Sheffield Scientists from the University of Sheffield have identified a new potential treatment pathway for cardiovascular disease. Their research has shown for the first time that a protein expressed in a subset of immune cells contributes towards the build-up of fatty deposits in arteries, which leads to cardiovascular disease. These fatty deposits...
Tag: <span>cardiovascular disease</span>
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Review links periodontitis to increased odds for hypertension
(HealthDay)—Periodontitis (PD) is a possible risk factor for hypertension, according to a review published online Sept. 24 in Cardiovascular Research. Eva Muñoz Aguilera, from University College London, and colleagues conducted a systematic review to examine the association between periodontitis and hypertension. Data from 40 studies were included in quantitative meta-analyses. The researchers found that diagnoses...
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A comprehensive atlas of genetic regulation of lipid metabolism published
UNIVERSITY OF HELSINKI An international research team has identified several novel genetic variants associated with plasma levels of lipid species and cardiovascular disease risk in humans. The study demonstrates that genetic studies focusing on circulating molecular lipid levels over traditional lipid measures can help improve cardiovascular risk prediction and treatment. The results of the study...
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What is an MTHFR mutation?
By Jamie Eske Reviewed by Shilpa Amin MD, CAQ, FAAFP Methylenetetrahydrofolate reductase, or MTHFR, is an enzyme that breaks down the amino acids homocysteine and folate. The MTHFR gene that codes for this enzyme has the potential to mutate, which can either interfere with the enzyme’s ability to function normally or completely inactivate it. People have...
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New study sheds light on novel exercise treatment for common form of cardiovascular disease
by Isabelle Dubach, University of New South Wales Weight training—also called resistance training—can help people with peripheral artery disease reduce painful symptoms like muscle cramps during walking, a study by UNSW medical researchers recently published in the British Journal of Sports Medicine has shown. In people with peripheral artery disease (PAD), a build-up of plaque in the arteries—caused by high cholesterol, nicotine and other cardiovascular disease risk factors—leads...
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Stopping statins may increase cardiovascular risk
By Maria Cohut Fact checked by Isabel Godfrey A large new study following thousands of participants found that older people who stop taking statins have a significantly increased risk of hospital admission due to cardiovascular problems. Statins are a class of drugs that people take to keep their blood cholesterol levels under control. Aside from this,...
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Early drug intervention reduces risk of cardiovascular events in rheumatoid arthritis sufferers
by Rebecca Biason, University of Toronto People who develop rheumatoid arthritis as older adults benefit from early and sustained use of a drug called Methotrexate (MTX), a recent study led by University of Toronto researcher Jessica Widdifield has found. The study, the first of its kind to examine the evidence around the effect of timing of MTX initiation in relation to long-term...
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Common foods linked to arterial stiffening in new metabolomics study
By Lois Zoppi, BA Reviewed by Kate Anderton, B.Sc. (Editor) Using untargeted metabolomics profiling, researchers have identified several lifestyle factors that could cause arteries to stiffen and increase the risk of heart disease. Whilst many of the factors -such as diabetes and high cholesterol – were already known, the researchers also identified two peptides commonly found in foods that may increase...
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Researchers discover how to treat diastolic heart failure
Research out of University Minnesota Medical School and published in the Journal of Clinical Investigation Insight uncovers what causes diastolic heart failure and how it can be treated. In the article, “Magnesium supplementation improves diabetic mitochondrial and cardiac diastolic function,” author Samuel Dudley, MD, Ph.D., Academic Chief of Cardiology at the University of Minnesota Medical...
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Expression of a molecule in blood cells predicts atherosclerosis risk
The receptor CD69 protects against the formation of atherosclerotic plaques CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III (F.S.P.) Earlier detection of cardiovascular disease is a step closer thanks to the findings of a research team at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) led by Francisco Sánchez-Madrid and Pilar Martín. The scientists have found that...