Katherine Lewin | News Reporter Novo Nordisk’s GLP-1 Wegovy has shown cardiovascular benefit again, this time in the Phase III STEP HFpEF trial, on top of the expected weight loss, the company announced at the European Society of Cardiology (ESC) Congress today. Against placebo, 2.4 mg of Wegovy (semaglutide) showed “large” reductions in heart failure-related...
Tag: <span>cardiovascular</span>
Tiny heart model offers game-changing potential for drug testing and cardiovascular disease treatments
by Hebrew University of Jerusalem Hand with microchip. Credit: Tissue Dynamics In a remarkable breakthrough, a collaborative team of researchers, led by Professor Yaakov Nahmias from The Hebrew University of Jerusalem, Technion-Israel Institute of Technology, and Tissue Dynamics Ltd., has unveiled a miniature human heart model that could potentially transform drug testing and cardiovascular research. This...
Investigating the laterality of blood pressure regulation during cardiovascular disease progression
by Thamarasee Jeewandara, Medical Xpress A schematic illustration of the lateralization during aortic baroreflex function. Credit: Journal of Hypertension (2023). DOI: 10.1097/HJH.0000000000003448 The outcomes of blood pressure regulation provide a clear picture of the underlying mechanisms of the arterial baroreflex, a critical cardiovascular reflex, during health and disease. Under normal blood pressure, the functional difference can vary between...
Dietary recommendations for cardiovascular health challenged by new evidence on saturated fatty acids’ effects on LDL-C and Lp(a) levels
A recent perspective piece published in The American Journal of Clinical Nutrition discussed current dietary recommendations to reduce the intake of saturated fatty acids and modulate the risk of cardiovascular disease while highlighting the impact of lower saturated fatty acid intake on low-density lipoprotein cholesterol (LDL-C) and lipoprotein A. Study: Lipoprotein(a) and Diet – A Challenge...
Researchers shed new light on damaging effects of standard heart attack treatment
by Indiana University School of Medicine Credit: Pixabay/CC0 Public Domain A study led by Indiana University School of Medicine is challenging standard treatment methods used to prevent muscle damage during heart attack. In a paper published in the Journal of the American College of Cardiology, Rohan Dharmakumar, Ph.D. asserts that a common treatment given to patients experiencing heart attack may...
FAST study finds no increased risk of cardiovascular events with febuxostat as compared with allopurinol for gout
by University of Glasgow Gout in X-ray of left foot. A major new study examining the relative safety of medicines for the treatment of gout will be presented at the American College of Rheumatology Convergence conference and will be published in The Lancet. The FAST Study finds no increased risk of cardiovascular events with febuxostat as compared...
Research pinpoints sources of atrial fibrillation
by Amy Colgan, The Ohio State University People who suffer from persistent atrial fibrillation in the heart may find relief from a new treatment approach discovered by researchers at The Ohio State University Davis Heart and Lung Research Institute. Atrial fibrillation is an irregular heartbeat, or a condition in which the atria fail to contract in a strong, rhythmic way....
Handgrip strength shown to identify people at high risk of type 2 diabetes
Findings demonstrate handgrip strength could be a cost-effective early screening tool A simple test such as the strength of your handgrip could be used as a quick, low-cost screening tool to help healthcare professionals identify patients at risk of type 2 diabetes. In new research, scientists at the universities of Bristol and Eastern Finland measured...
SGLT2 inhibitors can slow progression of chronic kidney disease
Two randomized controlled studies [1, 2] show: SGLT2 inhibitors can slow CKD progression in all patients, not only in patients with diabetes 850 million people worldwide are affected by chronic kidney disease (CKD) – a worrying figure, and one that continues to rise. Treatment options for patients with CKD are multiple and often determined by...
Study examines the heart risks and benefits of today’s most popular fad diets
Researchers examine claims associated with keto and intermittent fasting ANDREW M. FREEMAN, MD, IS A CARDIOLOGIST AT NATIONAL JEWISH HEALTH. DR. FREEMAN IS IN THE DIVISION OF CARDIOLOGY AND DEPARTMENT OF MEDICINE. view more CREDIT: NATIONAL JEWISH HEALTH In a review of existing scientific studies on trendy ketogenic and intermittent fasting diets, researchers at National...