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Big data initiative discovers new causal pathways in Alzheimer’s
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Big data initiative discovers new causal pathways in Alzheimer’s

by King’s College London Flowchart of study design. CTL, cognitively normal controls; MCI, mild cognitive impairment; AD, Alzheimer’s disease; Aβ, β-amyloid; CSF, cerebrospinal fluid; A, amyloid pathology; T, tau pathology; N, neurodegeneration; PRS, polygenic risk score; MR, mendelian randomization. Credit: Alzheimer’s & Dementia (2023). DOI: 10.1002/alz.12961 A new study, published on Feb. 15 in Alzheimer’s & Dementia, analyzed...