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Base editing shows potential superiority for curing sickle cell disease
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Base editing shows potential superiority for curing sickle cell disease

by St. Jude Children’s Research Hospital (L to R) Co-corresponding author Mitchell Weiss, M.D., Ph.D., St. Jude Department of Hematology chair and co-corresponding author Jonathan Yen, Ph.D., St. Jude Therapeutic Genome Engineering director at a microscope in the lab. Gene therapy that alters hemoglobin genes may be an answer to curing sickle cell disease (SCD) and...

Understanding sickle cell disease
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Understanding sickle cell disease

by Laurel Kelly  Credit: CC0 Public Domain Sickle cell disease, which is a group of inherited red blood cell disorders, affects approximately 100,000 people in the U.S., according to the Centers for Disease Control and Prevention. September is National Sickle Cell Awareness Month, which makes this a good time to learn about two of the...

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A new weapon in the fight against sickle cell disease

A technology developed initially at Case Western Reserve University is behind the global launch by a Portland, Oregon, company of a new, faster and low-cost diagnostic test for sickle cell disease (SCD). The announcement by Hemex Health comes just in advance of World Sickle Cell Disease Awareness Day. SCD is the most well-known among a...

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Snapshot of chikungunya could lead to drugs, vaccines for viral arthritis

by Tamara Bhandari,  Washington University School of Medicine in St. Louis Chikungunya virus, once confined to the Eastern Hemisphere, has infected more than 1 million people in the Americas since 2013, when mosquitoes carrying the virus were discovered in the Caribbean. Most people who become infected develop fever and joint pain that last about a week. But...