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3D Organization of DNA Controls Cell Identity Programs
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3D Organization of DNA Controls Cell Identity Programs

In a complex called chromatin, long strands of DNA in cells’ nuclei are tightly wrapped around a scaffolding of proteins, like a rolled-up ball of yarn. DNA – artistic interpretation.DNA – artistic interpretation. Image credit: Alius Noreika, created with Bing Image CreatorA new study by Weill Cornell Medicine investigators reveals that beyond providing a convenient...

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How Cell Identity is Preserved when Cells Divide

Posted Today MIT study suggests 3D folding of the genome is key to cells’ ability to store and pass on “memories” of which genes they should express. HeLa cells stained for nuclear DNA with the blue fluorescent Hoechst dye. On the left, a cell is going through mitosis and its DNA has condensed. Every cell in...