LEIBNIZ-FORSCHUNGSINSTITUT FÜR MOLEKULARE PHARMAKOLOGIE IMAGE: IN FED CELLS, EARLY ENDOSOMES FORM CONTACTS WITH ER TUBULES. TUBULAR ER MEMBRANES FACILITATE MITOCHONDRIAL FISSION AND SERVE AS SOURCE FOR LIPID DROPLET FORMATION. NUTRIENT STARVATION-INDUCED HYDROLYSIS OF ENDOSOMAL PI(3)P BY MTM1 REDUCES MEMBRANE CONTACTS BETWEEN THE TUBULAR ER AND EARLY ENDOSOMES. THE RESULTING LOSS OF PERIPHERAL ER TUBULES INDUCES...
