INSTITUTE OF INDUSTRIAL SCIENCE, THE UNIVERSITY OF TOKYO CREDIT: INSTITUTE OF INDUSTRIAL SCIENCE, THE UNIVERSITY OF TOKYO Tokyo, Japan – Type 1 diabetes mellitus (T1DM) results from an irreversible autoimmune destruction of insulin-producing pancreatic β-cells requiring life-long substitution of insulin. In a new study, researchers at the Institute of Industrial Science, The University of Tokyo...
Tag: <span>cell therapy</span>
CAR T cell therapy: potential for considerable savings
GERMAN CANCER RESEARCH CENTER (DEUTSCHES KREBSFORSCHUNGSZENTRUM, DKFZ) Chimeric antigen receptor (CAR) T cell therapy is a new and in some cases highly effective form of immunotherapy to treat certain types of cancer of the blood and lymph system. This promising treatment comes at a cost, however: The manufacturers charge up to EUR 320,000 for the...
Easier Way of Sneaking Antibodies into Cells
For almost any conceivable protein, corresponding antibodies can be developed to block it from binding or changing shape, which ultimately prevents it from carrying out its normal function. As such, scientists have looked to antibodies as a way of shutting down proteins inside cells for decades, but there is still no consistent way to get...
High-tech foam offers new tool for developing stem cells
Two Florida State University researchers are developing a high-tech material currently used in athletic equipment and prosthetics into a special tool to better develop stem cells. The work could improve drug screening, disease modeling, precision medicine, and cell therapy. FAMU-FSU College of Engineering researchers Yan Li, an associate professor in chemical and biomedical engineering, and...
First-ever US clinical trial of engineered iPSC-derived cell therapy for blood cancer
by University of Minnesota Medical School A new cancer clinical trial has opened at the M Health Fairview University of Minnesota Medical Center that leverages the groundbreaking research on stem cells and natural killer (NK) cells done at the Masonic Cancer Center and applies it to attack acute myeloid leukemia (AML) and B-cell lymphoma. The...
Green tea used as control trigger for activating cell therapies remotely
by Bob Yirka , Medical Xpress A team of researchers with East China Normal University and First Affiliated Hospital of Shenzhen University has found that it is possible to use green tea as a control mechanism for activating cell therapies remotely. In their paper published in the journal Science Translational Medicine, the group describes testing...
Decoding Cells to Unlock Stem Cells’ Potential
Posted Today Stem cells are jacks of all trades, capable of alleviating the consequences of such diverse pathologies as heart attacks, strokes and cancer. However, stem cell therapies have been hampered by possible side effects, which are frequently hard to predict. One way around this conundrum is to understand how stem cells conjure up their therapeutic...
CAR-T cell therapy and cancer
CAR-T therapy has proven to show good results in a range of patients both young and old. This type of immunotherapy teaches T cells to recognize and destroy cancer much more reliably. In some patients, this leads to the total elimination of cancer. There is also a significant amelioration of the disease in others. What...