Researchers at the University of Wisconsin–Madison and other institutions have harnessed a combination of lab-grown cells to regenerate damaged heart muscle.Mixing endothelial cells with heart muscle addresses major challenges of bringing treatments to the clinic. Image Credit: Yu-Che Cheng The study, published in Circulation, addresses major challenges of using heart muscle cells grown from stem...
Researchers have developed a technique that allows them to look simultaneously at a spatial level and at a genome-wide level at epigenetic mechanisms underlying tissue development, a breakthrough with multiple scientific and medical applications. While current technologies allow scientists to examine epigenetic information in the bulk of a tissue, and recent breakthroughs further extend to an individual...
HUBRECHT INSTITUTE IMAGE: STAINING FOR KRT15 AND COL17A1 IN THE HEALTHY HUMAN ESOPHAGEAL EPITHELIUM CREDIT: GEORG BUSSLINGER, COPYRIGHT HUBRECHT INSTITUTE Researchers from the group of Hans Clevers identified and characterized rare cell types in the upper gastrointestinal tract. Using single cell RNA sequencing, they studied the cellular composition of the esophagus, stomach and upper part of...
