The dying cells send signals to recipient tumor cells to increase aggressiveness, motility, and resistance to radiation or chemotherapy UNIVERSITY OF ALABAMA AT BIRMINGHAM BIRMINGHAM, Ala. – A surprising form of cell-to-cell communication in glioblastoma promotes global changes in recipient cells, including aggressiveness, motility, and resistance to radiation or chemotherapy.Paradoxically, the sending cells in this...
Tag: <span>Cell</span>
Post
Do You Know The 5 Types Of Stem Cells?
As you start to learn about stem cells, one of the most common questions to have is, “What types of stem cells exist?” Currently, there is not an agreed upon the number of stem cell types, because one can classify stem cells either by differentiation potential (what they can turn into) or by origin (from where they are sourced). While classifying stem cells by...
Post
Placental Stem Cells – The Rise of Placental Blood & Tissue Applications
Placental stem cells are a type of perinatal stem cell derived from the placental blood or tissue. In this interview with Dr. Ornella Parolini, Director of the E. Menni Research Center in Brescia, Italy, and President of the International Placenta Stem Cell Society (IPLASS), we discussed her pioneering research on human placental stem cells focused on...
Post
New epigenetic drug against Mantle Cell Lymphoma
New epigenetic drug against Mantle Cell Lymphoma A new study by doctor Manel Esteller, Director of the Epigenetics and Cancer Biology Program (PEBC) of the Bellvitge Biomedical ResearchInstitute (IDIBELL), ICREA Researcher and Professor of Genetics at the University of Barcelona, presents an epigenetic drug capable of slowing down cell growth in Mantle Cell Lymphoma (MCL), a...
Post
Some blood stem cells are better than others
UNIVERSITY OF SOUTHERN CALIFORNIA – HEALTH SCIENCES In your body, blood stem cells produce approximately 10 billion new white blood cells, which are also known as immune cells, each and every day. Even more remarkably, if some of these blood stem cells fail to do their part, then other blood stem cells pick up their...
Post
Definitive Guide to Perinatal Stem Cells
There are many types of perinatal stem cells, including those derived from the umbilical cord blood and tissue, placental blood and tissue, and the amnion and amniotic fluid. However, when stem cells were first identified, only two types of stem cells were described, adult stem cells and embryonic stem cells. The reason a diverse range of...
Post
Researchers Identify Essential Genes for Pluripotent Stem Cells Through CRISPR-Cas9 Screening
NEW YORK (GenomeWeb) – Researchers at the Hebrew University in Jerusalem, Israel have built a reference library of essential and growth-restriction genes in haploid human pluripotent stem cells (hPSCs) that they believe will reveal key aspects of cellular essentiality. In a study published yesterday in Nature, the researchers used a recently discovered group of haploid hPSCs to generate...
Post
Study changes long-held concepts of cell decoding
Scientists at the National Institute on Drug Abuse (NIDA) Intramural Research Program (IRP) have uncovered evidence that shows a more complex and elaborate role for the body’s hard-working G protein-coupled receptors (GPCRs) than previously thought, suggesting a conceptual advance in the fields of biochemistry and pharmacology. With more than 800 members in the human genome,...
Post
Study investigates how to turn stem cells into motor neurons
Stem cells can develop into many different types of cells, such as muscle cells, red blood cells, or neurons. Given their special regenerative ability, stem cells can be used to treat a wide range of diseases. A team of researchers uncovers new details involved in the process of turning stem cells into motor neurons. ...
Post
Inhibiting the SUMO Pathway Represses the Cancer Stem Cell Population in Breast and Colorectal Carcinomas
Highlights Sumoylation regulates CD44 and MMP14 expression in basal breast and colon cancer SUMO inhibition clears cancer stem cells, repressing invasiveness and tumor growth Anacardic acid functions as a SUMO inhibitor to repress cancer stem cells TFAP2A mediates anti-tumor effects of SUMO inhibition in breast and colon cancers Summary Many solid cancers have an expanded...