Tubulinopathies are a group of rare developmental and degenerative diseases that primarily affect the nervous system. While research has linked genetic mutations with these diseases, it’s less clear how these mutations specifically affect cells and trigger dysfunctions. In a new study, Yale scientists identify one particular genetic mutation that impairs brain cells. They also reveal the cellular...
Tag: <span>Cellular protein</span>
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How cellular protein factories may contribute to aging and age-related diseases
Research finds that the cellular assembly line that produces proteins can stall with age, triggering a snowball effect that increases the output of misfolded proteins. In humans, clumps of misfolded proteins contribute to age-linked Alzheimer’s and Parkinson’s diseases. Aging leads to a decline in cellular fitness and loss of optimal protein function. Many age-related ailments,...
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Cellular protein shredders for the fight against cancer
Study by the Universities of Bonn and Ulm investigates how a cellular mechanism can be used for other purposes UNIVERSITY OF BONN An international team of researchers led by the Universities of Bonn and Ulm has investigated how a cell’s own “protein shredder” can be specifically programmed to fight cancer. The researchers were able to...