by Ludwig Maximilian University of Munich The ASC speck is a central component of the NLRP3 inflammasome. Credit: iScience (2023). DOI: 10.1016/j.isci.2023.108382 A central component of the human immune system, the NLRP3 inflammasome plays an important role in fighting off infections. However, its chronic activation is also implicated in a variety of common diseases, such as...