CNRS If genetics is interested in gene sequencing, epigenetics studies how genes are going to be used, or not used, by a cell. The epigenome of a cell represents the set of chemical modifications of the DNA or associated proteins that will determine the expression of the genes and thus the cell’s identity. This information,...
Tag: <span>chemotherapies</span>
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Blood test offers early warning of chemotherapy-related heart problems
by Experimental Biology which chemotherapies can cause cardiotoxicity. The research team identified biomarkers and miRNAs that can provide early warning when this process is underway. Credit: Hari Vishal Lakhani, Marshall University Scientists have identified a collection of biomarkers that together signal that a person’s cancer treatment may be harming their heart. After further validation, the...
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Prior chemotherapies may impair ability to develop effective CAR T-cells
Pediatric patients with solid tumors may have poor quality T cells compared to patients with leukemia, and certain chemotherapies were detrimental to the T cells and their potential to become CAR T cells, according to data presented during a media preview for the AACR Annual Meeting 2018, April 14-18, in Chicago, Illinois. “The FDA approval of...
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New leukemia treatment outperforms standard chemotherapies
Researchers at ANU are working on a new treatment for an aggressive type of leukemia that outperforms standard chemotherapies. Lead researcher Dr Nadine Hein from The John Curtin School of Medical Research at ANU said researchers have successfully treated highly aggressive acute myeloid leukemia (AML) in mice using the new treatment. “Not only have we been able...