by University College Dublin 3D render of the tibias treated with the current clinical treatment option chemotherapeutics or treated with chemotherapeutics plus gene therapy. Post-treatment there is significantly more bone (purple) present following treatment with the novel therapeutics. Credit: Created with Biorender.com. New research has identified a potential therapeutic target and developed a unique delivery system...
THE UNIVERSITY OF BERGEN IMAGE: BENEDICTE SJO TISLEVOLL. PHOTO: JØRGEN BARTH, UIB CREDIT: PHOTO: JØRGEN BARTH, UIB Researchers from the University of Bergen, Norway, has found a new method that within hours can predict if certain cancer patients will survive or not after chemotherapy. Acute myeloid leukemia is an aggressive blood cancer with poor survival. Although...
by The Francis Crick Institute In vitro anticancer drug screen. a Volcano plots showing differences in IC50 values between RAS high and low CCLE cell lines. Drugs with enriched target annotations in the significant sensitive and resistant groups are highlighted (hypergeometric test) Drugs with an absolute log2 fold change >1 and fdr < 0.05 (linear model...
by University of Barcelona Credit: University of Barcelona Approximately 1 in 25 people will develop colon cancer during their lifetime and nearly 2 million cases new cases are diagnosed worldwide each year. Chemotherapy is commonly used to treat colon cancer. While this treatment is initially effective in most cases, many patients relapse after treatment. Led...
TEL-AVIV UNIVERSITY IMAGE: PROF. DAN PEER CREDIT: TEL AVIV UNIVERSITY Researchers from Tel Aviv University proved that a drug delivery system based on lipid nanoparticles can utilize RNA to overcome resistance to both chemotherapy and immunotherapy in cancer treatments. The study opens a new path to a personalized and precisely targeted battle against cancer. The...
by Institut du Cerveau (Paris Brain Institute) Fig. 1: HSCT causes the accumulation of brain parenchymal donor macrophages that become resident and surveillant. Credit: DOI: 10.1038/s41591-022-01691-9 More than 50,000 bone marrow-derived stem cell transplants are performed worldwide each year to treat a wide range of conditions, including brain diseases. Before the cells are transplanted, the...
GEORGIA INSTITUTE OF TECHNOLOGY IMAGE: RENDERING OF BRAIN/NEURONS FIRING (NIH) CREDIT: NIH Severe and persistent disability often undermines the life-saving benefits of cancer treatment. Pain and fatigue — together with sensory, motor, and cognitive disorders — are chief among the constellation of side effects that occur with the platinum-based agents used widely in chemotherapy treatments...
JANUARY 8, 2022 by Georgia Institute of Technology Rendering of brain/neurons firing (NIH). Credit: NIH Severe and persistent disability often undermines the life-saving benefits of cancer treatment. Pain and fatigue—together with sensory, motor, and cognitive disorders—are chief among the constellation of side effects that occur with the platinum-based agents used widely in chemotherapy treatments worldwide. A...
SWOG CANCER RESEARCH NETWORK The combination of dasatinib, blinatumomab, and prednisone can be effective in treating older patients with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) who are not good candidates for intensive chemotherapy treatment. These results from the S1318 clinical trial, led by the SWOG Cancer Research Network, a cancer clinical trials group funded...
By Rich Haridy November 22, 2021 Eremophila galeata is a small shrub that grows in arid areas of Western Australia Geoff DerrinCC BY-SA 4.0 Researchers have isolated a compound from an Australian desert shrub with a long history of medicinal use by the Indigenous peoples of Australia that could help cancer patients better respond to...
