PENN STATE UNIVERSITY PARK, Pa. — Previous research has found that chemotherapy can trigger muscle loss in people living with cancer, but a new study out of Penn State found it may also affect the way the body builds new muscle — and at lower doses than previously known, having potential implications for treatments and...
Tag: <span>Chemotherapy</span>
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Drug combination helps children with acute promyelocytic leukemia avoid conventional chemotherapy
A clinical trial has found that the combination of all-trans retinoic acid, which is a metabolite of vitamin A, and arsenic trioxide is highly effective in children with standard- and high-risk acute promyelocytic leukemia, or APL. Nearly all patients in the trial survived for two years without experiencing a relapse. None of the children with...
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Darolutamide showed similar benefits for Black patients as observed in the overall population
by American Association for Cancer Research Micrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia Black/African American patients with prostate cancer who were treated with the androgen receptor inhibitor darolutamide (Nubeqa) had clinical outcomes similar to those observed in the overall clinical trial population, according to results from the ARAMIS phase III...
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Cancer chemotherapy drug reverses Alzheimer’s symptoms in mice
by University of British Columbia Credit: Pixabay/CC0 Public Domain A drug commonly used to treat cancer can restore memory and cognitive function in mice that display symptoms of Alzheimer’s disease, new UBC research has found. The drug, Axitinib, inhibits the growth of new blood vessels in the brain—a feature shared by both cancer tumors and Alzheimer’s disease, but...
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Cancer patients on chemotherapy likely not fully protected by COVID-19 vaccine, study finds
by University of Arizona Health Sciences Credit: Unsplash/CC0 Public Domain The COVID-19 pandemic has been an especially stressful time for cancer patients undergoing chemotherapy, which attacks not only the cancer, but also the immune cells needed to defend the body from infections. New research at the University of Arizona Health Sciences found that patients undergoing...
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Some chemotherapy side effects caused by single mutation could be prevented
by Will Doss, Northwestern University Graphical abstract. Credit: DOI: 10.1016/j.stem.2021.08.006 Harmful side effects from a common chemotherapy drug could be the result of a single mutation, according to a study published in Cell Stem Cell. The cardiotoxic effects of the chemotherapy drug doxorubicin could be prevented in patients with the mutation by treating them with retinoic acid,...
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How the impact of chemotherapy on healthy cells affects the development of blood cells
by Institute for Research in Biomedicine (IRB Barcelona) Cancer (purple) patients exposed to chemotherapy, which damage cells DNA (orange stars), may develop treatment related acute myeloid leukimia (tAMLs). Non-malignant hematopoietic cells at the time of exposure to chemotherapy are faced with a bottleneck that reduces the population, leading to the development of AML over time. Credit:...
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Immunotherapy vs. chemotherapy
Immunotherapy and chemotherapy are common cancer treatments. Both use drugs to stop cancer from growing, but they achieve this in different ways. Immunotherapy enhances the immune system so it can target cancer cells. Chemotherapy directly acts on cancer cells, preventing them from replicating. Healthcare professionals may recommend a person undergo both treatments at the same...
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Successful test of ‘Trojan Horse’ cancer drug offers hope for an end to chemotherapy
By WILLIAM COLE FOR MAILONLINE PUBLISHED: 06:19 EDT, 31 May 2021 | UPDATED: 15:30 EDT, 31 May 2021 Researchers have successfully tested a new drug which can kill cancer cells without damaging nearby healthy tissue – removing the need for chemotherapy. Scientists at the University of Edinburgh combined the tiny cancer-killing molecule called SeNBD with a chemical food to trick the...
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Good bacteria can temper chemotherapy side effects
Naturally occurring gut bacteria can clean up chemo toxins in the body, study finds In the human gut, good bacteria make great neighbors. A new Northwestern University study found that specific types of gut bacteria can protect other good bacteria from cancer treatments — mitigating harmful, drug-induced changes to the gut microbiome. By metabolizing chemotherapy...