by John Innes Centre Compounds tested for their potential as antibiotics have demonstrated promising activity against one of the deadliest infectious diseases—tuberculosis (TB). Researchers from the John Innes Centre evaluated two compounds with antibacterial properties, which had been produced by the company Redx Pharma as antibiotic candidates, particularly against TB. TB, which is caused by...
Tag: <span>Chemotherapy</span>
A never-before-seen cell state may explain cancer’s ability to resist drugs
MEMORIAL SLOAN KETTERING CANCER CENTER Cancer’s knack for developing resistance to chemotherapy has long been a major obstacle to achieving lasting remissions or cures. While tumors may shrink soon after chemotherapy, many times they eventually grow back. Scientists once thought that unique genetic mutations in tumors underlay this drug resistance. But more and more, they...
A never-before-seen cell state may explain cancer’s ability to resist drugs
Cancer’s knack for developing resistance to chemotherapy has long been a major obstacle to achieving lasting remissions or cures. While tumors may shrink soon after chemotherapy, many times they eventually grow back. Scientists once thought that unique genetic mutations in tumors underlay this drug resistance. But more and more, they are casting their eyes on...
‘Wasabi Receptor’ Reveals Its Eye-Watering Secrets
Acrid smoke and fresh-chopped onions don’t have much in common — other than evoking an eye-watering urge to run to another room. Remarkably, the irritant chemicals in both smoke and onions — as well as garlic, horseradish and wasabi, and an assortment of potent toxins such as formaldehyde — all trigger this protective response by...
How to repair your gut
MONASH UNIVERSITY FLUORESCENT PICTURE OF AN INTESTINAL ORGANOID (STAINED FOR THE PROLIFERATION MARKER KI-67 (WHITE), THE STEM CELL MARKER EPHB2 (RED) AND DNA (BLUE). view more CREDIT: (C) MONASH BDI In a world first, Monash University researchers have identified a key biomolecule that enhances the repair of your gut lining by prompting stem cells to...
New nano drug candidate kills aggressive breast cancer cells
by Matt McGowan, University of Arkansas Chemical structure of multi-functional, anticancer drug candidate. Credit: Hassan Beyzavi, University of Arkansas. Researchers at the University of Arkansas have developed a new nano drug candidate that kills triple negative breast cancer cells. Triple negative breast cancer is one of the most aggressive and fatal types of breast cancer....
Scientists discover way to stop spread of devastating childhood cancer
Researchers at the University of East Anglia and the University of Manchester have made an important breakthrough that could lead to ‘kinder’ treatments for children with bone cancer, and save lives. Current treatment is grueling, with outdated chemotherapy cocktails and limb amputation. But despite all of this, the five-year survival rate is poor at just...
New forms of ‘red devil’ cancer drug could spare hearts
By Jocelyn KaiserJul. 1, 2020 , 1:20 PM Can the red devil be defanged? Doxorubicin, an old chemotherapy drug that carries this unusual moniker because of its distinctive hue and fearsome toxicity, remains a key treatment for many cancer patients. But a new study reports the drug can be tweaked to reduce its most punishing...
Targeting stem cells: The path to curing poor-prognosis leukaemia
Researchers at Children’s Cancer Institute have discovered what could prove a new and improved way to treat the poor-prognosis blood cancer, acute myeloid leukaemia or AML Researchers at Children’s Cancer Institute have discovered what could prove a new and improved way to treat the poor-prognosis blood cancer, acute myeloid leukaemia or AML. Unlike acute lymphoblastic...
Cancer vaccine hope: Personalised treatment designed to boost the body’s natural ability to fight the disease shows ‘promising signs’ in clinical trials
By RYAN MORRISON FOR MAILONLINE Researchers take a biopsy of a cancerous tumour to look for certain proteins Each patient has a ‘different cancer’ and the treatment is specifically targeted It is given alongside chemotherapy drugs to boost the body’s immune response So far only eight per cent of patients saw their tumour reduce but...