HOKKAIDO UNIVERSITY A compound effective in killing chemotherapy-resistant glioblastoma-initiating cells (GICs) has been identified, raising hopes of producing drugs capable of eradicating refractory tumors with low toxicity. Despite longstanding and earnest endeavors to develop new remedies, the prognosis of most glioblastoma patients undergoing chemotherapies and radiotherapies remains poor. Glioblastoma, a malignant glioma, has a median...
Tag: <span>Chemotherapy</span>
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Cancer patients who exercise have less heart damage from chemotherapy
EUROPEAN SOCIETY OF CARDIOLOGY Sophia Antipolis, 07 October 2019: Patients with cancer should receive a tailored exercise prescription to protect their heart, reports a paper published today in the European Journal of Preventive Cardiology, a journal of the European Society of Cardiology (ESC).1 ‘Cancer patients are often less active than adults without cancer,’ said author Dr Flavio D’Ascenzi, University of Siena, Italy. ‘However, exercise is essential for patients diagnosed with cancer who are under...
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FAK protein linked to chemotherapy resistance in ovarian cancer
UNIVERSITY OF CALIFORNIA – SAN DIEGO Although the number of women being diagnosed and dying of ovarian cancer is declining, recurrence, drug resistance and mortality remain high for women with high-grade serous ovarian carcinoma, the most common form of epithelial ovarian cancer. A new study in the journal eLife by University of California San Diego School...
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How might the keto diet help treat cancer?
By Ana Sandoiu Fact checked by Jasmin Collier New research in mice suggests that keeping blood sugar under control using either the ketogenic diet or a diabetes drug could help treat certain cancers by boosting the efficacy of standard chemotherapy. The ketogenic diet consists of high fat foods, foods that contain an adequate amount of...
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Living with advanced breast cancer
Sponsored Content by Eisai This article is intended for Healthcare Professionals Breast Cancer ProgramIOB Institute of Oncology An interview with Dr Javier Cortes, Head of Breast Cancer Program, IOB Institute of Oncology, Madrid and Barcelona, Spain. When does breast cancer become “advanced”? There is a certain amount of debate surrounding the exact definition of advanced breast cancer (ABC). When we talk about clinical trials, it’s not easy to...
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Two-in-one drug combining Herceptin with chemotherapy keeps women’s breast cancers at bay
by Institute of Cancer Research Guiding chemotherapy to a tumour by attaching it to the antibody-based target drug Herceptin (trastuzumab) is effective at treating women with breast cancer who have no other treatment options, a new clinical trial shows. The two-in-one treatment kept breast cancer at bay in women with a type of the disease called HER2-positive breast cancer who had stopped responding to existing drugs. As well as being effective in women with high HER2...
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Unresolved injury, not fibrosis, contributes to cisplatin-induced CKD
by Julie Parry, Yale University Yale School of Medicine researchers have found that the progression of acute kidney injury to chronic kidney disease (CKD) caused by use of the chemotherapy drug cisplatin is due to unresolved injury and sustained activation of regulated necrosis pathways rather than fibrosis. The new study is highlighted on the cover of...
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Chemical added to consumer products impairs response to antibiotic treatment
Grocery store aisles are stocked with products that promise to kill bacteria. People snap up those items to protect themselves from the germs that make them sick. However, new research from Washington University in St. Louis finds that a chemical that is supposed to kill bacteria is actually making them stronger and more capable of...
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Purdue cancer identity technology makes it easier to find a tumor’s ‘address’
Improved drug delivery method is aimed at making chemotherapy easier to help treat people with various tumors. PURDUE UNIVERSITY WEST LAFAYETTE, Ind. – Purdue University researchers have developed a technology aimed at making it easier to deliver cancer treatment to the right “address” in the body while also easing the painful side effects of chemotherapy...
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Open source machine learning tool could help choose cancer drugs
The selection of a first-line chemotherapy drug to treat many types of cancer is often a clear-cut decision governed by standard-of-care protocols, but what drug should be used next if the first one fails? That’s where Georgia Institute of Technology researchers believe their new open source decision support tool could come in. Using machine learning...