by Lisbeth Heilesen, Aarhus University New knowledge about cholesterol contribute to the understanding of the neurodegenerative Niemann-Pick type C disease – also called “childhood Alzheimer’s” Credit: Mikael WinklerUsually, the word “cholesterol” prompts a negative reaction because of its role in cardiovascular disease. While this is true, cholesterol is also vital for cells to function correctly—for...
Tag: <span>cholesterol</span>
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New Pill Cuts Cholesterol and Heart Attacks
By Nisha Zahid New Pill Cuts Cholesterol and Heart Attacks. Credit: Daniel Foster, CC BY-NC-SA A new cholesterol-lowering drug called Nexletol has shown promise in reducing the risk of heart attacks and other cardiovascular problems in people who cannot tolerate traditional statin drugs, according to a major study presented at the American College of Cardiology’s annual meeting....
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Arterial stiffness may cause metabolic syndrome in adolescents via an increase in fasting insulin and LDL cholesterol
by University of Eastern Finland The presence of any three of high blood pressure, high trunk fat mass, high fasting glucose, high fasting triglyceride and low fasting high-density lipoprotein cholesterol describes metabolic syndrome. Arterial stiffness in adolescents measured with carotid-femoral pulse wave velocity may potentially cause metabolic syndrome in young adulthood via an increase in fasting...
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Study: Cholesterol substantially reduced with oral PCSK9 inhibitor
by Graciela Gutierrez, Baylor College of Medicine Atherosclerosis of the heart’s arteries reduces surface area and oxygen carrying capacity. Credit: http://www.scientificanimations.com/Wikimedia Commons, CC BY-SA A new study led by Baylor College of Medicine and presented at the American College of Cardiology’s Annual Scientific Session together with World Congress of Cardiology found that an oral PCSK9 inhibitor called...
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Study: Opioid drug tolerance develops from interplay of key gene and cholesterol
by Stacey DeLoye, University of Florida An “unbiased” screen for genes involved in opioid tolerance relied upon tiny worms called C. elegans. The worm genetics revealed PTCHD1 plays a key role, altering cholesterol in cell membranes. Credit: Scott Wiseman for UF Scripps Biomedical Research. UF Scripps Biomedical Research scientists have a discovered a key gene that...
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Unhealthy cholesterol linked to long COVID and other prolonged illnesses
by King’s College London Space-filling model of the Cholesterol molecule. Credit: RedAndr/Wikipedia Scientists from King’s working on the ZOE Health Study analyzed blood markers from 4,787 people and found that participants who had higher levels of harmful fats commonly linked to heart disease, were more likely to experience ongoing symptoms from both COVID-19 and non-COVID disease....
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DOCTORS GENE-EDIT PATIENT’S LIVER TO MAKE LESS CHOLESTEROL
A team of researchers from US biotech company Verve Therapeutics have injected a gene-editing serum into a live patient’s liver with the goal of lowering their cholesterol, a watershed moment in the history of gene editing that could potentially save millions from cardiovascular disease and heart attacks, MIT Technology Review reports. The clinical trial kicked off with a patient...
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Drinker’s sex plus brewing method may be key to coffee’s link to raised cholesterol
by British Medical Journal Credit: CC0 Public Domain The sex of the drinker as well as the brewing method may be key to coffee’s link with raised cholesterol, a known risk factor for heart disease, suggests research published in the open access journal Open Heart. Drinking espresso was associated with the widest gender difference in cholesterol level; plunger (cafetière)...
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DRUG THAT ‘SCOOPS UP’ CHOLESTEROL MAY CUT DEMENTIA RISK AFTER STROKE
The research team investigated cyclodextrin, which is FDA-approved for use as an ingredient in other drugs. Cyclodextrin’s chemical properties and shape allow it to “scoop up” and safely store cholesterol without provoking a heightened inflammatory response. The researchers found that treatment with cyclodextrin resulted in less cholesterol accumulation and inflammation in the brain in animal...
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What to know about cholesterol for hair
Cholesterol is a fatty substance that plays an important role in certain areas of the body, including the skin and hair. Cholesterol is a waxy, fatty substance present in many animals, including humans. People can also use this substance in external treatments for areas such as the body and hair. Cholesterol treatments may help seal...