Tag: <span>cholesterol</span>

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Study: Cholesterol substantially reduced with oral PCSK9 inhibitor
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Study: Cholesterol substantially reduced with oral PCSK9 inhibitor

by Graciela Gutierrez, Baylor College of Medicine Atherosclerosis of the heart’s arteries reduces surface area and oxygen carrying capacity. Credit: http://www.scientificanimations.com/Wikimedia Commons, CC BY-SA A new study led by Baylor College of Medicine and presented at the American College of Cardiology’s Annual Scientific Session together with World Congress of Cardiology found that an oral PCSK9 inhibitor called...

Study: Opioid drug tolerance develops from interplay of key gene and cholesterol
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Study: Opioid drug tolerance develops from interplay of key gene and cholesterol

by Stacey DeLoye,  University of Florida An “unbiased” screen for genes involved in opioid tolerance relied upon tiny worms called C. elegans. The worm genetics revealed PTCHD1 plays a key role, altering cholesterol in cell membranes. Credit: Scott Wiseman for UF Scripps Biomedical Research. UF Scripps Biomedical Research scientists have a discovered a key gene that...

Unhealthy cholesterol linked to long COVID and other prolonged illnesses
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Unhealthy cholesterol linked to long COVID and other prolonged illnesses

by  King’s College London Space-filling model of the Cholesterol molecule. Credit: RedAndr/Wikipedia Scientists from King’s working on the ZOE Health Study analyzed blood markers from 4,787 people and found that participants who had higher levels of harmful fats commonly linked to heart disease, were more likely to experience ongoing symptoms from both COVID-19 and non-COVID disease....

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DOCTORS GENE-EDIT PATIENT’S LIVER TO MAKE LESS CHOLESTEROL

A team of researchers from US biotech company Verve Therapeutics have injected a gene-editing serum into a live patient’s liver with the goal of lowering their cholesterol, a watershed moment in the history of gene editing that could potentially save millions from cardiovascular disease and heart attacks, MIT Technology Review reports. The clinical trial kicked off with a patient...

Drinker’s sex plus brewing method may be key to coffee’s link to raised cholesterol
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Drinker’s sex plus brewing method may be key to coffee’s link to raised cholesterol

by British Medical Journal Credit: CC0 Public Domain The sex of the drinker as well as the brewing method may be key to coffee’s link with raised cholesterol, a known risk factor for heart disease, suggests research published in the open access journal Open Heart. Drinking espresso was associated with the widest gender difference in cholesterol level; plunger (cafetière)...

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DRUG THAT ‘SCOOPS UP’ CHOLESTEROL MAY CUT DEMENTIA RISK AFTER STROKE

The research team investigated cyclodextrin, which is FDA-approved for use as an ingredient in other drugs. Cyclodextrin’s chemical properties and shape allow it to “scoop up” and safely store cholesterol without provoking a heightened inflammatory response. The researchers found that treatment with cyclodextrin resulted in less cholesterol accumulation and inflammation in the brain in animal...

What to know about cholesterol for hair
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What to know about cholesterol for hair

Cholesterol is a fatty substance that plays an important role in certain areas of the body, including the skin and hair. Cholesterol is a waxy, fatty substance present in many animals, including humans. People can also use this substance in external treatments for areas such as the body and hair. Cholesterol treatments may help seal...

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Grape consumption benefits gut microbiome and cholesterol metabolism

Fresno, CA – A new clinical study published in the scientific journal Nutrients found that consuming grapes significantly increased the diversity of bacteria in the gut which is considered essential to good health overall.  Additionally, consuming grapes significantly decreased cholesterol levels, as well as bile acids which play an integral role in cholesterol metabolism.  The findings suggest...

Study provides structural insights into how cholesterol in the brain regulates ion channels and alters their function
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Study provides structural insights into how cholesterol in the brain regulates ion channels and alters their function

by  The Mount Sinai Hospital Space-filling model of the Cholesterol molecule. Credit: RedAndr/Wikipedia Through a structural and functional approach, researchers from the Icahn School of Medicine at Mount Sinai and Stanford University Medical Center identified physical binding sites for cholesterol in the brain’s G-protein-gated inwardly rectifying potassium (GIRK) channels, potassium channels that have been implicated in a variety...

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Cholesterol-lowering statins prescribed less later in day

UNIVERSITY OF PENNSYLVANIA SCHOOL OF MEDICINE Furthering efforts to understand why potentially life-saving statins are so under-prescribed among American patients with heart disease, a new study shows that clinicians are more likely to sign a script for them earlier in the day. The new study by researchers in Penn Medicine’s Nudge Unit found that patients with the...