by Stacey DeLoye, University of Florida An “unbiased” screen for genes involved in opioid tolerance relied upon tiny worms called C. elegans. The worm genetics revealed PTCHD1 plays a key role, altering cholesterol in cell membranes. Credit: Scott Wiseman for UF Scripps Biomedical Research. UF Scripps Biomedical Research scientists have a discovered a key gene that...
by King’s College London Space-filling model of the Cholesterol molecule. Credit: RedAndr/Wikipedia Scientists from King’s working on the ZOE Health Study analyzed blood markers from 4,787 people and found that participants who had higher levels of harmful fats commonly linked to heart disease, were more likely to experience ongoing symptoms from both COVID-19 and non-COVID disease....
A team of researchers from US biotech company Verve Therapeutics have injected a gene-editing serum into a live patient’s liver with the goal of lowering their cholesterol, a watershed moment in the history of gene editing that could potentially save millions from cardiovascular disease and heart attacks, MIT Technology Review reports. The clinical trial kicked off with a patient...
by British Medical Journal Credit: CC0 Public Domain The sex of the drinker as well as the brewing method may be key to coffee’s link with raised cholesterol, a known risk factor for heart disease, suggests research published in the open access journal Open Heart. Drinking espresso was associated with the widest gender difference in cholesterol level; plunger (cafetière)...
The research team investigated cyclodextrin, which is FDA-approved for use as an ingredient in other drugs. Cyclodextrin’s chemical properties and shape allow it to “scoop up” and safely store cholesterol without provoking a heightened inflammatory response. The researchers found that treatment with cyclodextrin resulted in less cholesterol accumulation and inflammation in the brain in animal...
Cholesterol is a fatty substance that plays an important role in certain areas of the body, including the skin and hair. Cholesterol is a waxy, fatty substance present in many animals, including humans. People can also use this substance in external treatments for areas such as the body and hair. Cholesterol treatments may help seal...
Fresno, CA – A new clinical study published in the scientific journal Nutrients found that consuming grapes significantly increased the diversity of bacteria in the gut which is considered essential to good health overall. Additionally, consuming grapes significantly decreased cholesterol levels, as well as bile acids which play an integral role in cholesterol metabolism. The findings suggest...
by The Mount Sinai Hospital Space-filling model of the Cholesterol molecule. Credit: RedAndr/Wikipedia Through a structural and functional approach, researchers from the Icahn School of Medicine at Mount Sinai and Stanford University Medical Center identified physical binding sites for cholesterol in the brain’s G-protein-gated inwardly rectifying potassium (GIRK) channels, potassium channels that have been implicated in a variety...
UNIVERSITY OF PENNSYLVANIA SCHOOL OF MEDICINE Furthering efforts to understand why potentially life-saving statins are so under-prescribed among American patients with heart disease, a new study shows that clinicians are more likely to sign a script for them earlier in the day. The new study by researchers in Penn Medicine’s Nudge Unit found that patients with the...
by American Heart Association Credit: CC0 Public Domain Testing how well “good” cholesterol particles reduce inflammation may help predict who is at heightened risk to develop cardiovascular disease caused by narrowed arteries, according to research published today in the American Heart Association’s flagship journal Circulation. Assessing levels of high-density lipoprotein (HDL) cholesterol, known as “good cholesterol,” are already a...
