by Dennis Thompson Statins have become the miracle medicine of modern heart care, lowering cholesterol levels and and guarding against heart attacks in millions of Americans. In fact, a running joke among doctors holds that statins are so helpful they should be put in the water supply. However, they aren’t right for all patients, and...
Tag: <span>cholestrol</span>
New study shows a role for cholesterol in pain perception
Pressure on cells reduces pain signals, but excess cholesterol can interfere, researchers findPeer-Reviewed Publication UF HEALTH IMAGE: A CELL MEMBRANE IS ILLUSTRATED TO SHOW THE SURFACE IN RED. BLUE OBJECTS ARE PROTEINS, INCLUDING ION CHANNELS, WHICH CAN SEND ELECTRICAL IMPULSES INTO CELLS. LIPIDS, OR FATS, ARE IN YELLOW. IN THIS CROSS SECTION, AN ION CHANNEL...
First trial of ‘base editing’ in humans lowers cholesterol — but raises safety concerns
Super-precise gene-editing approach switches off a gene in the liver that regulates ‘bad’ cholesterol. Miryam Naddaf Cholesterol crystals (red) in a lipid droplet in a human liver.Credit: Steve Gschmeissner/Science Photo Library The first trial in humans of the precise gene-editing technique known as base editing has shown promising results for keeping cholesterol levels in check....
An updated test measures how well ‘good cholesterol’ works
by NIH/National Heart, Lung and Blood Institute Graphical abstract. Credit: Journal of Clinical Investigation (2023). DOI: 10.1172/JCI165370High-density lipoprotein (HDL) cholesterol, often called “good cholesterol,” removes extra cholesterol from the arteries by gobbling up early-forming plaque and transporting it to the liver, which flushes it out of the body. It’s an essential job: when too much plaque...