Tag: <span>chromosomal abnormality</span>

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Chromosomal chaos promotes therapy resistance in leukemia cells and opens up new treatment approaches

by German Cancer Research Center CK-AML is characterized by different modes of clonal dynamics and ongoing instability. Credit: Nature Genetics (2024). DOI: 10.1038/s41588-024-01999-x Chromosomal instability plays a crucial role in the progression of cancer: it shapes the properties of tumor cells and drives the development of therapy resistance. Scientists from the German Cancer Research Center (DKFZ), the Heidelberg...

UTHSC researchers’ work on human pangenome aids understanding of common chromosomal abnormality
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UTHSC researchers’ work on human pangenome aids understanding of common chromosomal abnormality

UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER IMAGE: UTHSC RESEARCHERS CONTRIBUTED TO THE LANDMARK HUMAN PANGENOME DRAFT REFERENCE, WHICH WAS PUBLISHED ALONGSIDE THEIR BIOLOGICAL DISCOVERY REGARDING A COMMON CHROMOSOMAL ABNORMALITY. CREDIT: COURTESY UTHSC Researchers from the University of Tennessee Health Science Center have made a foundational discovery about chromosome biology through their work on the first-ever human...