Tag: <span>Chromosome</span>

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Loss of Y chromosome in men enables cancer to grow
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Loss of Y chromosome in men enables cancer to grow

CEDARS-SINAI MEDICAL CENTER  IMAGE: DAN THEODORESCU, MD, PHD, DIRECTOR OF CEDARS-SINAI CANCER, THE PHASE ONE DISTINGUISHED CHAIR CREDIT: CEDARS-SINAI MEDICAL CENTER As men age, some of their cells lose the very thing that makes them biological males—the Y chromosome—and this loss hampers the body’s ability to fight cancer, according to new research from Cedars-Sinai Cancer. The study, published...

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Another Medical cold case cracked by the MUHC’s ‘Dr. House’

A team from the Research Institute of the McGill University Health Centre (RI-MUHC) led by Dr. Donald Vinh, the RI’s so-called “Dr. House” because of his research into rare diseases, has discovered a new human disease and the gene responsible for it, paving the way for the proper diagnosis of patients globally and the development...

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Breakthrough in understanding Warsaw breakage syndrome

Unraveling the action of the DDX11/CHLR1 helicase enzyme in DNA repair TOKYO METROPOLITAN UNIVERSITY Researchers from Tokyo Metropolitan University and the FIRC Institute of Molecular Oncology (IFOM) in Italy have uncovered a previously unknown function of the DDX11 helicase enzyme. Mutations in the gene which codes for DDX11 are known to be implicated in Warsaw Breakage...

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Hi-C Maps Used to Inexpensively Generate Chromosome-Length Genome Assemblies

COLD SPRING HARBOR, NY (GenomeWeb) – By relying on the Hi-C approach to map interactions between chromatin regions, researchers have been able to assemble de novo mammalian genomes for less than $1,000. Olga Dudchenko, a postdoc in Erez Lieberman Aiden’s lab at the Baylor College of Medicine, said during her talk at the Biology of Genomes meeting here that...