by Karolinska Institutet Credit: Unsplash/CC0 Public DomainChronic kidney disease (CKD) affects more than 10% of adults worldwide. Mental health is an important yet under-recognized issue in patients with CKD. Depression is common and related to poor prognosis in CKD patients, but previous research has primarily focused on dialysis patients, leading to an insufficient understanding of depression...
Tag: <span>Chronic Kidney Disease</span>
Heart failure causally linked to chronic kidney disease
by Elana Gotkine Heart failure is causally associated with chronic kidney disease (CKD), according to a study published online Dec. 11 in PLOS ONE. Junyu Zhang, from Hunan University of Chinese Medicine in Changsha, China, and colleagues used data from European populations, including 930,014 controls and 47,309 cases of heart failure from the HERMES consortium...
Could statins reduce death risk in chronic kidney disease?
Statin use was linked to a lower death risk in kidney disease in a new study. Image credit: Comezora/Getty Images. A statin was the most prescribed drug in the United States in 2020, and guidance is continually being updated recommending the expansion of the use of this type of drug. Initially prescribed in the late...
Nephrology researchers investigate treatment options for impaired physical performance in chronic kidney disease
by Liam Connolly, UC Davis Graphical abstract. Credit: JCI Insight (2023). DOI: 10.1172/jci.insight.167274 Nephrology researchers at UC Davis Health are shining a light on chronic kidney disease (CKD) as they investigate treatment options for impaired physical performance and exercise intolerance in chronic kidney disease patients. Led by Baback Roshanravan, associate professor of medicine and the Paul F. Gulyassy...
Transcription factor prevents bone frailty in chronic kidney disease
by Melissa Rohman, Northwestern University Genetic overexpression of Hnf4α2 in osteoblasts prevents bone loss in mice with chronic kidney disease. Microtomography analysis of femur cortical bone at metaphysis and at midshaft in 20-week-old wild-type mice. Credit: Northwestern University Northwestern Medicine investigators have discovered that the overexpression of a transcription factor prevented bone loss in mouse models...
Link between chronic kidney disease and cardiovascular disease explained
TOKYO MEDICAL AND DENTAL UNIVERSITY CREDIT: DEPARTMENT OF NEPHROLOGY, TMDU Researchers from Tokyo Medical and Dental University (TMDU) have uncovered a link between cardiovascular disease and chronic kidney disease, revealing novel disease biomarkers and therapeutic targets Tokyo, Japan – Chronic kidney disease is linked to the formation of mineral deposits on blood vessel walls, known as...
Higher urine-to-plasma urea ratio reflects heightened risk of chronic kidney disease progression
by National Kidney Foundation Credit: Pixabay/CC0 Public Domain In a large cohort of patients with common forms of chronic kidney disease (CKD), researchers found that urine-to-plasma ratio of urea ([U/P]urea) was independently associated with CKD progression and kidney failure. An association of urinary concentrating capacity with CKD progression, independently of glomerular filtration rate (GFR), supports the notion...
New onset chronic kidney disease in people with diabetes highest among ethnic, racial minorities
UNIVERSITY OF CALIFORNIA – LOS ANGELES HEALTH SCIENCES New onset chronic kidney disease (CKD) in people with diabetes is highest among racial and ethnic minority groups compared with white persons, a UCLA-Providence study finds. The study, published as a letter to the editor in the New England Journal of Medicine, found that new onset CKD rates...
Simple blood and urine test can help patients with chronic kidney disease
by University of Glasgow Credit: Unsplash/CC0 Public Domain New research, led by the University of Glasgow and published in the British Journal of General Practice, assessed patient data from across the U.K. and found that not enough people with chronic kidney disease were routinely being given this recommended test. The study results have prompted renewed calls...
Analysis reveals sex differences in the recognition, monitoring and treatment of chronic kidney disease
by American Society of Nephrology Credit: Unsplash/CC0 Public Domain New research published in JASN reveals profound sex differences in the detection, monitoring, and management of chronic kidney disease (CKD) in Sweden. Efforts to ensure equitable care between sexes could have important implications in reducing the burden of CKD in the country and elsewhere. Worldwide, there are sex differences...