by Steve Graff, University of Pennsylvania For Mark Paviglianiti, it started in 1962 when he was just six years old. While he lay in bed sick for weeks with a fever, doctors from his hometown of Lancaster, Pennsylvania, worked to figure out what was wrong. Eventually, they spotted high levels of protein in his urine—a surefire sign...
Tag: <span>Chronic kidney disease(CKD)</span>
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Kidney disease linked to increased risk of falling
by Marc Ransford, Ball State University Kidney disease causes middle-aged people to be as susceptible to falling as older adults, say researchers from Ball State University. “Epidemiology of falls and fall-related injuries among middle-aged adults with kidney disease” recently published by the journal International Urology and Nephrology, found that people with chronic kidney disease (CKD) were at increased risk of...
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PCSK9 inhibitors: Specific studies are mandatory to prove efficacy and safety in CKD
ERA-EDTA Chronic kidney disease (CKD) is associated with a substantially increased risk for the development of atherosclerotic cardiovascular disease (CVD). Accordingly, cardiovascular mortality is increased even in the earliest stages of CKD. In the general population and in CKD patients, high plasma levels of low-density lipoprotein cholesterol (LDL-C) are crucially involved in the initiation and progression of atherosclerotic...
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Unresolved injury, not fibrosis, contributes to cisplatin-induced CKD
by Julie Parry, Yale University Yale School of Medicine researchers have found that the progression of acute kidney injury to chronic kidney disease (CKD) caused by use of the chemotherapy drug cisplatin is due to unresolved injury and sustained activation of regulated necrosis pathways rather than fibrosis. The new study is highlighted on the cover of...
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Sugar-sweetened beverage pattern linked to higher kidney disease risk
Higher collective consumption of sweetened fruit drinks, soda, and water was associated with a higher likelihood of developing chronic kidney disease (CKD) in a community-based study of African-American adults in Mississippi. The findings, which appear in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN), contribute to the growing body...
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Metabolites altered in chronic kidney disease
Chronic kidney disease (CKD) affects 1 in 7 people in the United States, according to the U.S. National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK). These individuals have a very high risk of cardiovascular disease, and some will also progress to kidney failure requiring dialysis and transplantation. However, few options exist to treat...
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Research connects first-time kidney stone formers and chronic kidney disease
Kidneys (stock image). Getting your first kidney stone may put you a risk for chronic kidney disease, say researchers. Mayo Clinic nephrologists have uncovered a connection between first-time kidney stone formers and chronic kidney disease. In a paper published in Mayo Clinic Proceedings, researchers announce a persistent decline in kidney functioning following an individual’s first case...