by Stellenbosch University South Africa Credit: Unsplash/CC0 Public Domain Two landmark clinical trials reported at the Union Conference in Paris showed that an oral antibiotic taken for six months once-daily substantially reduced the risk of developing drug-resistant TB. The antibiotic levofloxacin safely reduced the risk of multidrug-resistant (MDR) tuberculosis (TB) disease in children by 56%,...
by University of Birmingham AOC3 activity relative to baseline. Mean AOC3 activity relative to baseline versus time curves after once daily administration of 1 mg, 3 mg, 6 mg or 10 mg BI 1467335 or placebo for up to 85 days (whole profile days at Day 1, 28 and 84; FAS). Error bars show standard deviation from the mean. Source...
by University College London Credit: samer daboul from PexelsA new drug candidate, based on pioneering UCL and Moorfields Eye Hospital research and currently under development by SIFI S.p.A., has been found to be highly effective in treating a rare sight-threatening eye infection in a new international clinical trial. The findings, published in Ophthalmology, describe the efficacy...
By Michael Irving October 23, 2023 A diabetes-delaying drug has shown promise in a new clinical trialDepositphotosA phase 3 clinical trial has shown that a drug called teplizumab can slow down progression of type 1 diabetes in children and teenagers with a recent diagnosis. The trial’s success could help expand the options for patients and relieve...
UNIVERSITY OF CALIFORNIA – SAN DIEGO IMAGE: MOST OF THE RESEARCH INVOLVED IN THE SAMARA STUDY WILL TAKE PLACE AT THE ALTMAN CLINICAL AND TRANSLATIONAL RESEARCH INSTITUTE, PICTURED ABOVE, LOCATED AT JACOBS MEDICAL CENTER AT UC SAN DIEGO HEALTH. view more CREDIT: UC SAN DIEGO HEALTH According to the National Institutes of Health, approximately 24%...
A clinical trial of an experimental universal influenza vaccine developed by researchers at the National Institute of Allergy and Infectious Diseases’ (NIAID) Vaccine Research Center (VRC), part of the National Institutes of Health, has begun enrolling volunteers at Duke University in Durham, North Carolina. This Phase 1 trial will test the experimental vaccine, known as...
Reviewed by Emily Henderson, B.Sc. May 3, 2023 Researchers from the University of Oxford have reported findings from a Phase 2 clinical trial investigating the efficacy of an investigational treatment against long COVID fatigue. The study (reported in Lancet eClinical Medicine) found participants given the treatment, developed by US pharmaceutical company Axcella Therapeutics, reported feeling less fatigued than...
By Michael Irving March 21, 2023 An endoscopy procedure could help slow or prevent the progression of type 2 diabetes, suggests a new clinical trial Depositphotos A phase 2 clinical trial is currently exploring a new technique to slow the progression of type 2 diabetes. The simple outpatient surgery can be conducted in the early...
BY CHARLES PILLER These MRI images show brain swelling in the cerebral cortex—the outer large section of the brain—of a Florida woman who died after receiving the experimental Alzheimer’s drug lecanemab. Before treatment with the antibody, a scan of her cerebral cortex (left) reveals characteristic folds of the temporal lobes. Afterward (right), extreme swelling made...
IMAGE SOURCE, NHSBT Image caption, The lab-grown blood kept in a facility in BristolBy James GallagherHealth and science correspondent Blood that has been grown in a laboratory has been put into people in a world-first clinical trial, UK researchers say. Tiny amounts – equivalent to a couple of spoonfuls – are being tested to see...
