A first-in-human, Phase 1 trial assessing the safety and immunogenicity of an investigational nanoparticle influenza vaccine designed to provide long-lasting protection against multiple flu virus strains has begun at the National Institutes of Health Clinical Center in Bethesda, Maryland. Healthy participants 18 to 50 years old will receive either a licensed seasonal influenza vaccine or...
by Andrea Greif, Leukemia & Lymphoma Society Bone marrow aspirate showing acute myeloid leukemia. Several blasts have Auer rods. Patients participating in The Leukemia & Lymphoma Society’s (LLS) groundbreaking precision medicine Beat AML Master Clinical Trial had superior outcomes compared to acute myeloid leukemia (AML) patients who opted for standard chemotherapy treatment, according to findings...
by University of Chicago Medical Center The findings, simultaneously published in the New England Journal of Medicine and presented at the American Society of Nephrology’s Kidney Week 2020 conference, show the investigational drug finerenone had tangible renal and cardiovascular benefits for patients with chronic kidney disease and type 2 diabetes. The 5,700-person phase III trial was led by...
MASSACHUSETTS GENERAL HOSPITAL BOSTON – An experimental medication that was recently shown to slow the progression of the neurodegenerative disease amyotrophic lateral sclerosis (ALS), or Lou Gehrig’s disease, has now demonstrated the potential to also prolong patient survival. The findings come from a clinical trial conducted by investigators at the Sean M. Healey & AMG...
by Duke University Medical Center A new drug offers hope for young boys with the progressive neuromuscular disease Duchenne muscular dystrophy (DMD) by potentially offering an alternative to high-dose glucocorticoids that have significant side effects. Interim results from a 24-month clinical trial at Duke Health and other institutions suggest that the drug, vamorolone, may retain or...
Antibiotic resistance is a major obstacle that modern medicine is currently grappling with. It has created crisis situations around the world, and researchers are trying to find solutions. One clinical trial is now breaking the superbug barrier. Bacteria can cause a range of infections, and sometimes the best way to fight off these stubborn “bugs” is by using...
