by Institute for Basic Science The inflammatory response of RA causes autophagy in FLSs to produce putrescine, which intensifies inflammation of GABA and H2O2 through the MAO-B in the joint. In chronic inflammation, increased IL-1β passes through a loose blood-brain barrier and enters the brain. Increased IL-1β in the hippocampus causes cognitive impairment by activating astrocytes...
by University of Toronto Credit: Pixabay/CC0 Public Domain A new nationally representative study published online in the Journal of Alzheimer’s Disease Reports found hearing impairment and vision impairment to be independently associated with cognitive impairment. After considering sex, age and other socio-demographic characteristics, older adults with hearing impairment had more than double the odds of cognitive impairment, while those with vision...
by Craig Brierley, University of Cambridge Credit: Pixabay/CC0 Public Domain Cognitive impairment as a result of severe COVID-19 is similar to that sustained between 50 and 70 years of age and is the equivalent to losing 10 IQ points, say a team of scientists from the University of Cambridge and Imperial College London. The findings,...
by Eric Adler Credit: CC0 Public Domain For people of a certain age, it takes only a few “senior moments”—struggling for words, names or memories—to cause worry. Is this normal aging or mild cognitive impairment(MCI)? Is it all a run-up to Alzheimer’s? As a neuropsychologist at the University of Kansas Medical Center-Wichita, Ryan Schroeder conducts the...
by Baylor College of Medicine Credit: CC0 Public Domain Alzheimer’s disease (AD), the most common type of dementia, progressively impairs memory, concentration and the ability to learn new things and accomplish everyday activities. Although scientists do not yet fully understand the causes of cognitive impairment associated with AD, a group of researchers at Baylor College...
Pauline Anderson February 14, 2022 A high level of education, superior academic performance and excellent written language skills may predict the reversal of mild cognitive impairment (MCI) to normal cognitive function, new research shows. Investigators found individuals with these factors, which are all markers of cognitive reserve, had a significantly greater chance of reversion from MCI to...
MASSACHUSETTS GENERAL HOSPITAL BOSTON – Certain brain wave patterns that occur while an individual sleeps may be assessed by clinicians to help them diagnose dementia and other conditions related to memory, language, and thinking. A new study published in Sleep that was led by investigators at Massachusetts General Hospital (MGH) and Beth Israel Deaconess Medical Center (BIDMC) could...
by IOS Press Credit: CC0 Public Domain A new nationally representative study published online in the Journal of Alzheimer’s Diseasefound an abrupt decline in the prevalence of cognitive impairment among American adults aged 65 and older compared to the same age group a decade earlier. In 2008, 12.2 percent of older Americans reported serious cognitive problems. In...
by Cara Murez (HealthDay)—A diagnosis of mild cognitive impairment (MCI) might worry an older adult, who could see it as a stepping stone to dementia. But a new study suggests one does not necessarily lead to the other. In fact, nearly half of seniors tracked in the study—all of who had been diagnosed with issues...
by Davide Bruno, Andrew Rutherford, The Conversation Credit: Oleksandr Osipov/Shutterstock The potential long-term neurological effects of concussions and other knocks to the head in professional sport have attracted significant attention and research interest over recent years. Confirmation in 2014 that former England footballer Jeff Astle died as a result of chronic traumatic encephalopathy (a form of dementia)—and that it...
