by Maddie Massy-Westropp, University of New South Wales Credit: Pixabay/CC0 Public Domain They’re integral to summer, as ubiquitous as a zinced-up nose or a backyard cricket game. From December onward, walk into any gathering and processed meats are being served. It’s the bacon sizzling on the barbecue, the cured ham at Christmas lunch and the...
by Fred Hutchinson Cancer Center Cancer — Histopathologic image of colonic carcinoid. Credit: Wikipedia/CC BY-SA 3.0 A comprehensive analysis of more than 100,000 colorectal cancer (CRC) cases, led by researchers at the Fred Hutchinson Cancer Center in Seattle and 200 scientific collaborators worldwide, has identified more than 100 new genetic risk factors strongly linked with...
by American College of Surgeons Non-invasive, less expensive test is effective in early-stage colorectal cancer screening. Credit: American College of Surgeons Commercially available noninvasive screening tests for colorectal cancer—a fecal immunochemical test (FIT) and the multi-target stool DNAtest (mt-sDNA; or Cologuard®)—are equally effective for screening patients with early-stage colorectal cancer. However, a FIT costs about...
CITY OF HOPE IMAGE: DR. MARWAN FAKIH, CO-DIRECTOR OF CITY OF HOPE’S GASTROINTESTINAL CANCER PROGRAM, HAS IDENTIFIED A NOVEL COMBINATION IMMUNOTHERAPY REGIMEN THAT DEMONSTRATED SIGNIFICANT RESPONSE IN A SUBGROUP OF PEOPLE WITH RECURRENT METASTATIC COLORECTAL CANCER. CREDIT: CITY OF HOPE LOS ANGELES — A physician-scientist at City of Hope, one of the largest cancer research and...
by Rémi Carlier, Ecole Polytechnique Federale de Lausanne POU5F1B differs from OCT4. a Representative immunofluorescence–confocal microscopy of POU5F1B-HA overexpressing SW480 cells, with DAPI in blue, HA in pink, and the nuclear membrane marker lamin-B1 in green. Two fields out of eight are shown. b Immunohistochemistry for endogenous POU5F1B in adjacent normal colon and primary colon...
by Perelman School of Medicine at the University of Pennsylvania Cancer — Histopathologic image of colonic carcinoid. Credit: Wikipedia/CC BY-SA 3.0 A molecule produced in the liver in response to low-carb “ketogenic” diets has a powerful effect in suppressing colorectal tumor growth and may be useful as a preventive and treatment of such cancers, according...
by H. Lee Moffitt Cancer Center & Research Institute To perform a spatial ecological analysis the team developed a new tool called VALIS that aligns histology slides, making it possible to construct highly multiplexed images from tissues stained via immunohistochemistry (IHC) and/or immunofluorescence. This image shows one of the 11-plex IHC used in the spatial...
MASSACHUSETTS GENERAL HOSPITAL BOSTON — New clinical research shows that lamivudine, a reverse transcriptase inhibitor widely used in HIV therapy, stopped disease progression in 25% of patients with fourth-line metastatic colorectal cancer. Findings from the trial, published in Cancer Discovery, raise the possibility of an unexpected promising direction in cancer treatment, not just colorectal cancer. The trial included...
by Rice University Rice University bioengineer Omid Veiseh with a vial of bead-like implants his lab invented to serve as anti-cancer drug factories. Veiseh and colleagues showed the implants could eradicate ovarian and colorectal cancer in mice in as little as six days. Credit: “Jeff Fitlow/Rice University” Rice University bioengineers have shown they can eradicate...
by Oxford University Press Cancer — Histopathologic image of colonic carcinoid. Credit: Wikipedia/CC BY-SA 3.0 A new paper in JNCI Cancer Spectrum, published by Oxford University Press, indicates that overweight and obese people who lose weight may reduce their chances of later developing colorectal adenoma—a type of benign growth or polyp in the colon or rectum...
