by Queen’s University Belfast Graphical Abstract SynLeGG utilizes MultiSEp gene expression clusters to partition CRISPR essentiality scores (top) and mutations from whole exome sequencing (bottom), in order to predict candidate genetic dependency relationships, including synthetic lethality. Credit: Nucleic Acids Research (2021). DOI: 10.1093/nar/gkab338 In a groundbreaking first, research led by Queen’s University Belfast has found thousands of “Achilles Heels’ or ‘cancer...
