by Lauren Quinn, University of Illinois at Urbana-Champaign Finasteride decreases plaque size and macrophage content in Ldlr-/- mice. Four-week-old male Ldlr-/- mice were fed Western diet with increasing doses of finasteride for 12 weeks. Two days before tissue harvesting, mice were injected with EdU to track monocyte trafficking into the atherosclerotic lesions. (A) En face visualization...
