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Source of common kidney disease lies outside the kidney, study suggests
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Source of common kidney disease lies outside the kidney, study suggests

by Columbia University Irving Medical Center Cross-ancestry GWAS for IgAN. Credit: Nature Genetics (2023). DOI: 10.1038/s41588-023-01422-x The cause of a common kidney disease likely lies outside the kidney, according to a new study led by Columbia University researchers. The study, which uncovered 16 new locations in the genome linked to immunoglobulin A (IgA) nephropathy, confirms an earlier hypothesis that...

Study illuminates sugar’s role in common kidney disease
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Study illuminates sugar’s role in common kidney disease

by University of Washington School of Medicine An illustration shows fluid absorption and cyst expansion in kidney organoids infected with polycystic kidney disease (PKD). The outward-facing proximal tubular epithelial cells (green) absorb fluid, generating pressure that causes expansion and stretching of the epithelium, creating cysts. It is unclear why normal epithelial cells resist cyst formation....