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While the brain acquires resistance to continuous treatment with mGluR5 inhibitor drugs, lasting effects may still arise
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While the brain acquires resistance to continuous treatment with mGluR5 inhibitor drugs, lasting effects may still arise

While the brain acquires resistance to continuous treatment with mGluR5 inhibitor drugs, lasting effects may still arise if dosing occurs intermittently and during a developmental-critical period. Mark Bear, Picower Professor of Neuroscience at MIT, recalls the “eureka moment” 20 years ago when he realized that a severe developmental brain disorder — fragile X syndrome —...