by Radiological Society of North America Visualization of attention maps from the residual attention networks for the inspiratory convolutional neural network (I-CNN) and expiratory convolutional neural network (E-CNN) models. Attention maps highlight regions of the input image contributing to the network’s predictions. Low-level features (minor details, such as texture) and high-level features (major details, such as...
Tag: <span>COPD</span>
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First new treatment for asthma and COPD in half a century—new study
by Mona Bafadhel, Richard Russell and Sanjay Ramakrishnan, The Conversation Credit: Pixabay/CC0 Public Domain Every 30 seconds, someone in the world will experience a flare-up of their asthma or chronic obstructive pulmonary disease (COPD) symptoms. For decades, the standard treatment for these potentially life-threatening episodes has remained unchanged—treatment with steroids, such as prednisolone. Unfortunately, these drugs don’t...
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Small RNAs might drive COPD progression: Research lays foundation for potential new diagnostics and therapies
by Roni Dengler, Thomas Jefferson University Graphical abstract. Credit: Molecular Therapy—Nucleic Acids (2024). DOI: 10.1016/j.omtn.2024.102285 Chronic obstructive pulmonary disease (COPD) affects nearly 12 million people in the U.S. alone and is the third leading cause of death worldwide. High levels of immune molecules known as cytokines, which can damage the lungs, are a hallmark of COPD. Now, molecular...
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Childhood neglect associated with later stroke, COPD, cognitive impairment, and depression
by University of Toronto Credit: Unsplash/CC0 Public Domain New research from the University of Toronto found that childhood neglect, even in the absence of childhood sexual abuse and physical abuse, is linked with a wide range of mental and physical health problems in adulthood. “While a large body of research has established the detrimental impact of childhood physical...
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Inhaler misuse leads to mismanagement of COPD symptoms, increased exacerbations
News Release 20-Aug-2024 Patients need additional education on proper inhaler use to improve outcomes Peer-Reviewed PublicationCOPD Foundation MIAMI (August 20, 2024) – Inhaler misuse leading to inadequate medication delivery impacts a person’s ability to manage symptoms of chronic obstructive pulmonary disease (COPD), and additional education about proper inhaler use is needed to improve health outcomes,...
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Genetics of COPD important for lung function in young people, study finds
August 13, 2024 by Karolinska Institutet Box plot of variance in FEV1/FVC explained by the PRS for airflow limitation across the lifespan. Credit: eClinicalMedicine (2024). DOI: 10.1016/j.eclinm.2024.102731Certain genetic variants that have previously been linked to the lung disease COPD can explain reduced lung function already in children and adolescents, according to researchers at Karolinska Institutet....
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COPD improved by tweaks to microbiome via fecal transplant or diet
By Paul McClure COPD symptoms were alleviated by a healthier gut microbiome Depositphotos Improving the health of the gut microbiome by way of fecal transplant (in mice) and dietary modification (in humans), has been shown by researchers to noticeably improve COPD symptoms. The finding could lead to microbiome-targeted treatments that provide relief to people suffering from...
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Gabapentinoids associated with severe exacerbation of COPD
by American College of Physicians Credit: Pixabay/CC0 Public DomainA population-based cohort study of more than 10,000 persons using gabapentinoids found that their use was associated with an increased risk of chronic obstructive pulmonary disease (COPD) exacerbation. This study supports the warnings from regulatory agencies and highlights the importance of considering this potential risk when prescribing gabapentin...
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Beetroot juice supplement found to lower blood pressure, improve exercise capacity in people with COPD
by European Respiratory Society Credit: Pixabay/CC0 Public Domain A 12-week course of daily beetroot juice supplement for people with chronic obstructive pulmonary disease (COPD) lowered blood pressure and improved how far patients could walk in six minutes in research published in the European Respiratory Journal. COPD is a serious lung condition affecting around 400 million...
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Protein discovery raises prospect of treatment for COPD
By Paul McClure Researchers have discovered a protein associated with antiviral defense can exacerbate COPDDepositphotos A new study has found that TLR7, a protein that normally triggers our immune system to defend against certain viruses, plays a pivotal role in exacerbating chronic obstructive pulmonary disease or COPD. The unexpected discovery may lead to new therapeutic approaches...