by London School of Hygiene & Tropical Medicine Credit: CC0 Public Domain Prolonged use of corticosteroids, such as prednisolone, has been shown to cause osteoporosis and therefore increases the risk of breaking a bone. The more corticosteroids are taken, the greater the damage can be. In individuals with prolonged corticosteroid use, especially in older age, fracture preventive measures are...
AMERICAN SOCIETY OF HEMATOLOGY (WASHINGTON, April 26, 2022) — People with sickle cell disease (SCD) who were recently prescribed a corticosteroid – a medicine frequently used to treat asthma or inflammation – were found to be significantly more likely to be hospitalized for a severe pain event, according to a paper published today in the journal Blood. The...
By Akanksha Singh, BDS. Reviewed by Danielle Ellis, B.Sc. Corticosteroids have been advised as a drug to target the host immune response in patients affected with severe lung inflammation due to coronavirus disease 2019 (COVID-19). This treatment has been beneficial in reducing the mortality rate significantly. Corticosteroids have been in use for over 70 years and...
by McGill University Health Centre Credit: Pixabay/CC0 Public Domain Despite high hopes, a new pan-Canadian study published today in The BMJ suggests that ciclesonide—an inhaled and nasal steroid drug commonly used for asthma and rhinitis—won’t be the treatment to change the course of the pandemic. The results of this first placebo controlled trial of inhaled steroids for...
by George Institute for Global Health Distributions of the Primary Outcome and Time to Death Curves to Day 90 A, Life support was defined as invasive mechanical ventilation, circulatory support, or kidney replacement therapy. There were missing data in 11 patients for the primary outcome. Red represents the worse outcomes and blue represents better outcomes. B,...
INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) Approximately 5% of people with Covid-19 progress to a severe or critical form, including the development of severe pneumonia that progresses to acute respiratory distress syndrome. While these forms sometimes occur early in the course of the disease, clinical observations generally describe a two-stage...
New data show advantage of add-on therapy with belimumab in lupus nephritis Systemic lupus erythematosus (SLE) is a chronic, inflammatory, autoimmune disease, in which damage is caused to multiple organs and tissues by the formation and deposition of immune complexes (antigen-antibody complexes). The kidneys are also affected in about half of the patients when immune...
(HealthDay)—For adults with exacerbation of chronic obstructive pulmonary disease (COPD), antibiotics and systemic corticosteroids are associated with less treatment failure, according to a review published online Feb. 25 in the Annals of Internal Medicine. Claudia C. Dobler, M.D., Ph.D., from the Mayo Clinic in Rochester, Minnesota, and colleagues assessed the comparative effectiveness and adverse events...
