by Liu Jia, Chinese Academy of Sciences Credit: Public Domain Depression, a common mental disorder, can severely disturb the life of its patients. A hypothesis stated that the excitatory synapses characterized by the post-synaptic density (PSD) in the hypothalamus, which played a crucial role in emotion regulation, may be involved in the pathogenesis of depression. However,...
Corticotropin–releasing hormone (CRH), also called corticotropin–releasing factor (CRF), is a peptide hormone that activates the synthesis and release of adrenocorticotropic hormone (ACTH) from the pituitary gland. In this way, CRH affects our response to stress, addiction and depression, among others. What is Corticotropin-Releasing Hormone? CRH is a neuropeptide hormone that regulates neuroendocrine, sympathetic, and behavioral functions in response to stress. It consists of 41 amino acids...
