by Children’s Hospital Boston SARS-CoV-2 (shown here in an electron microscopy image). Credit: National Institute of Allergy and Infectious Diseases, NIH A study led by researchers at Boston Children’s Hospital explains for the first time why COVID-19 causes severe inflammation in some people, leading to acute respiratory distress and multi-organ damage. Surprisingly, the study also...
by Tulane University Tracy Fischer, PhD, lead investigator and associate professor of microbiology and immunology at the Tulane National Primate Research Center. Credit: Tulane University, Paula Burch-Celentano COVID-19 patients commonly report having headaches, confusion and other neurological symptoms, but doctors don’t fully understand how the disease targets the brain during infection. Now, researchers at Tulane...
Interview conducted by Emily Henderson, B.Sc.Mar 30 2022 Thought LeadersDr. Ahmed G. IbrahimAssistant Professor, Smidt Heart InstituteCedars-Sinai Medical Center In this interview, we speak to Dr. Ahmed G. Ibrahim about his latest research that has discovered a new possible treatment for COVID-19. Please could you introduce yourself and tell us what inspired your latest research into...
by Iqbal Pittalwala, University of California – Riverside David Lo. Credit: University of California – Riverside The Biden administration is planning to give Americans age 50 or older the option of a second booster. But is a second booster necessary? Would it differ from the first booster? And who should receive the second booster first?...
by Cornell University Credit: Pixabay/CC0 Public Domain A newly discovered small molecule could be sprayed into people’s noses to prevent COVID-19 illness prior to exposure and provide early treatment if administered soon after infection, according to a study in mice led by Cornell University researchers. The study, published in Nature, employed experimental mice engineered with human receptors...
by The Peter Doherty Institute for Infection and Immunity Establishment of S751-specific CD4+ T cell memory following mild COVID-19. a, Frequency of TET751+ cells (as a percentage of total CD4+) among uninfected (n = 9) or COVID-19 convalescent individuals sampled 20 to 60 d after symptom onset (n = 19). The lines indicate the median, and bars indicate the IQR. b, Representative...
SCIENCE CHINA PRESS IMAGE: OVEREXPRESSION OF CLYBL COULD LEAD TO THE LOSS OF UPSTREAM METABOLITES, THUS RESULTING IN THE REDUCTION OF ITACONATE. ITACONATE CAN INHIBIT SUCCINATE DEHYDROGENASE (SDH), ACTIVATE NRF2/NFE2L2 VIA ALKYLATION OF KEAP1, AND INHIBIT CASPASE-1-MEDIATED CLEAVAGE OF IL-1Β AND IL-18 TO AVOID EXCESSIVE INFLAMMATION VIA THE BLOCKAGE OF NLRP3 INFLAMMASOME ACTIVATION. CREDIT: ©SCIENCE...
by Society of Nuclear Medicine Figure 1. 18F-FDG PET in COVID-19–related CNS disorders: Principal components analysis of spatial covariance pattern (first row) and statistical parametric mapping analysis of metabolic group differences (second to fifth rows) in patients with COVID-19–related encephalopathy, patients with post-COVID-19 syndrome, and patients with post-COVID-19 syndrome and hyposmia compared to healthy controls (n=13)....
By Ashley Nash March 10, 2022 12:50 p.m. MST This undated electron microscope image made available by the U.S. National Institutes of Health in February 2020 shows the virus that causes COVID-19. Researchers at Thomas Jefferson University are developing a treatment for people who have lost their smell due to COVID-19. NIAID-RML via Associated Press Researchers at Thomas...
by Emily Head, Imperial College London Credit: Shutterstock Long-lasting immune activity in the airways might be the cause of persistent breathlessness following COVID-19. This is according to a new study of 38 people who were previously hospitalized with severe COVID-19. The results, published in Immunity, suggest these patients have an altered landscape of immune cells in their airways...
