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How to redesign COVID vaccines so they protect against variants
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How to redesign COVID vaccines so they protect against variants

Ewen Callaway &  Heidi Ledford People await coronavirus vaccines at a hospital in Glasgow, UK.Credit: Jeff J. Mitchell/Getty As evidence grows that new variants of the SARS-CoV-2 coronavirus can evade immunity produced by vaccines or previous infections, scientists are exploring the idea of redesigning the vaccines currently being rolled out worldwide. Researchers are still debating whether...

Novavax offers first evidence that COVID vaccines protect people against variants
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Novavax offers first evidence that COVID vaccines protect people against variants

Ewen Callaway &  Smriti Mallapaty Novavax’s protein-based vaccine relies on tried-and-tested technology. Credit: PA Images/Alamy The biotech firm Novavax has unveiled that its experimental vaccine is effective against rapidly spreading variants of the coronavirus. But its data bring good news and bad news: although the vaccine was more than 85% effective against a COVID-19 variant...

How anti-ageing drugs could boost COVID vaccines in older people
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How anti-ageing drugs could boost COVID vaccines in older people

COVID-19 poses the greatest threat to older people, but vaccines often don’t work well in this group. Scientists hope drugs that rejuvenate the immune system will help. Older adults, like these nursing-home residents in Spain, are more vulnerable to infection and can respond poorly to vaccines. Unlike fine wine, the human body does not improve...