News Release 25-Sep-2024 Researchers reviewed the recent therapeutic developments and upcoming challenges of CRISPR-Cas13, a cutting-edge RNA-editing technology Peer-Reviewed PublicationNanjing Agricultural University The Academy of Science In recent years, the scientific community has made significant strides in the field of gene editing, particularly through the development of the CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)...
Tag: <span>CRISPR-Cas13</span>
Post
CRISPR-Cas13 technique targets proteins causing ALS and Huntington’s disease in the mouse nervous system
by Liz Ahlberg Touchstone, University of Illinois at Urbana-Champaign Spinal cord astrocytes, the cells seen in this fluorescent microscope image, are involved in the progression of ALS. A new CRISPR-Cas13 system targeting mutant protein production in these cells improved outcomes for mice with ALS. Credit: Thomas Gaj and Colin Lim A single genetic mutation can...
Post
RNA Editing Possible with CRISPR-Cas13
Scientists extend the capabilities of the CRISPR-Cas system to include precise manipulations of RNA sequences in human cells. Fusing an RNA-editing enzyme to an RNA-targeting Cas protein has enabled researchers to edit specific nucleotides within RNA molecules in human cells. The approach, called RNA Editing for Programmable A-to-I replacement (REPAIR), is described today (October 25)...