Some researchers hoping that gene-editing technology can conquer forms of Alzheimer’s caused by genetic mutations. Tosin Thompson A laboratory-grown cell that produces amyloid precursor protein. Such cells are cultured for use in Alzheimer’s research.Credit: Simon Fraser/Science Photo Library Last month saw the first-ever approval of a gene therapy that uses the CRISPR–Cas9 gene-editing tool, a...
By Meeri Kim February 5, 2022 at 9:00 a.m. EST Paddy Doherty remembers his father as a proud, hard-working family man who stayed physically fit for most of his life. A career in construction and various home improvement projects kept him active until his 60s, when Doherty first caught glimpses of a worrying decline in...
Structure of the gene editing enzyme Cas9 interacting with guide RNA and DNA (PDB ID: 4OO8). Source: Gabriel Velez (Mahajan Lab) As CRISPR-Cas9 starts to move into clinical trials, a new study published in Nature Methods has found that the gene-editing technology can introduce hundreds of unintended mutations into the genome. “We feel it’s critical that the...
