Tag: <span>Crispr</span>

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Screening the dark genome for disease

IMAGE: THIS IS CHARLES GERSBACH, THE ROONEY FAMILY ASSOCIATE PROFESSOR OF BIOMEDICAL ENGINEERING AT DUKE UNIVERSITY.   Researchers have developed a method to swiftly screen the non-coding DNA of the human genome for links to diseases that are driven by changes in gene regulation. The technique could revolutionize modern medicine’s understanding of the genetically inherited risks...

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U.S. science advisory committee supports genetic modification of human embryos

Embryos could soon be edited—but there are some caveats. Ever since CRISPR—the relatively cheap and easy-to-use genome editing technique—made its way to the scientific stage, researchers have grappled with one of its biggest ethical quagmires: Its ability to edit human embryos, thereby potentially altering the DNA of subsequent generations. The question of whether to allow such a...

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Controlling CRISPR: Researchers May Have Found An “Off-Switch” for Gene-Editing

IN BRIEF Researchers have uncovered two distinct anti-CRISPR proteins — AcrIIA2 and AcrIIA4 — that worked to inhibit the ability of SpyCas9 to target specific genomes in bacteria. The discovery could lead to an “off switch” for CRISPR that would give scientists greater control over the gene editing tool when using it in human subjects....

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Scientists discover the gene editing ‘off-switch’ that could protect against accidents or stop it from being used for harm

  Researchers found proteins that are ‘potent inhibitors’ against Crispr-Cas9 Anti-Crispr proteins make procedure more precise to prevent an accident And, it would also provide a ‘fail safe’ if the technology falls in the wrong hands In recent years, the use of gene editing techniques has raised concern among both scientists and the public, with some...

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