by University of Cambridge High magnification micrograph of Crohn’s disease. Biopsy of esophagus. H&E stain. Credit: Nephron/WikipediaA large-scale clinical trial of treatment strategies for Crohn’s disease has shown that offering early advanced therapy to all patients promptly after diagnosis can drastically improve outcomes, including by reducing the number of people requiring urgent abdominal surgery for treatment...
by King’s College London Micrograph showing inflammation of the large bowel in a case of inflammatory bowel disease. Colonic biopsy. Credit: Wikipedia/CC BY-SA 3.0New King’s College London research reveals that interventions that improve mood can reduce levels of inflammation in people with inflammatory bowel disease by 18%, compared to having no mood intervention. Researchers at the...
AbbVie’s Skyrizi helps more Crohn’s patients stay off steroids than J&J’s Stelara, PhIII data showAyisha SharmaNews ReporterAbbVie’s Skyrizi has demonstrated significantly higher rates of steroid-free clinical and endoscopic remission versus rival Johnson & Johnson’s Stelara in a Phase III trial, helping set the Crohn’s disease drug apart in an increasingly competitive market. Stelara won an...
The cells that line the gut of an ulcerative colitis patient are inflamed and filled with a protein called PAI-1 (shown in red) that is linked to blood clotting. Nuclei are shown in blue, and other intestinal cells are marked in green. Researchers at Washington University School of Medicine in St. Louis have found that blocking the...
