Tag: <span>Crohn’s disease (CD)</span>

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Crohn’s Disease Disturbs the Immune Properties of Human Adipose-Derived Stem Cells Related to Inflammasome Activation

Highlights •ASCs isolated from CD patients are highly proliferative, invasive, and phagocytic •Proliferative ASCs may be responsible for the development of creeping fat •ASCs from CD patients have dampened immunosuppressive properties •Selection of the best immunosuppressive ASCs for cell therapy is advocated Summary Crohn’s disease (CD) is characterized by the expansion of mesenteric fat, also...

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Azathioprine appears to improve disease course in early Crohn’s

(HealthDay)—Long-term use of azathioprine (AZA) is associated with a better disease course in patients with early Crohn’s disease (CD), according to a study published online Sept. 22 in the Journal of Gastroenterology and Hepatology. Yun Qiu, from Sun Yat-sen University in China, and colleagues evaluated the impact of AZA on disease progression in a cohort of 190 patients with...