Using cryo-electron microscopy, researchers at Case Western Reserve University School of Medicine and National Institutes of Health open door to new level of detail in study of abnormal proteins that cause untreatable neurodegenerative conditions The highest-ever resolution imaging of an infectious prion provides the first atomic-level data of how these abnormal proteins are assembled to cause fatal...
Tag: <span>cryo-electron microscopy</span>
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Ball-and-chain inactivation of ion channels visualized by cryo-electron microscopy
by Weill Cornell Medical College Ion channels, which allow potassium and sodium ions to flow in and out of cells, are crucial in neuronal ‘firing’ in the central nervous system and for brain and heart function. These channels use a “ball-and-chain” mechanism to help regulate their ion flow, according to a new study led by...