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Scientists discover new role for bile acids: They curb appetite by entering the brain
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Scientists discover new role for bile acids: They curb appetite by entering the brain

by  Ecole Polytechnique Federale de Lausanne Neuronal cell line (mHypoE-N41) transfected with NPY-mCherry (in red) and stained with phalloidin to label the actin cytoskeleton (in green). In this cell TGR5 was activated by its selective agonist INT-777 and this activation caused the stabilization and polymerization of the actin fibers (green) and the consequent accumulation of NPY...