by La Jolla Institute for Immunology This scanning electron microscope image shows SARS-CoV-2 (round blue objects) emerging from the surface of cells cultured in the lab. As scientists around the world develop life-saving COVID-19 vaccines and therapies, many are still wondering exactly why the disease proves deadly in some people and mild in others. To solve...
Tag: <span>cytotoxic</span>
HDAC6 can control tumor growth and halt metastasis in triple-negative breast cancer
by George Washington University Genetic modifier HDAC6 was found to control tumor growth and halt metastasis in triple-negative breast cancer in vivo, according to a new study published in the top-tier journal Cancer Research by investigators at the George Washington University (GW) Cancer Center. Immunotherapy—the use of drugs to stimulate one’s own immune system to...
Mapping the immune landscape of hematological cancers may help to enhance therapies
by University of Helsinki Activating the immune system is a promising form of cancer treatment. Researchers at the University of Helsinki and Helsinki University Hospital as well as the University of Eastern Finland mapped out the immune landscape of hematological malignancies in a dataset covering more than 10,000 patients to identify drug targets and patient...
Marine alga from the Kiel Fjord discovered as a remedy against infections and skin cancer
GEOMAR research group successfully applies bioinformatics methods and machine learning in marine drug discovery HELMHOLTZ CENTRE FOR OCEAN RESEARCH KIEL (GEOMAR) BALTIC SEA SEAWEED FUCUS VESICULOSUS AND ITS FUNGAL SYMBIONT WERE INVESTIGATED IN THIS STUDY. view more CREDIT: LARISSA BÜDENBENDER Healing with the help of marine organisms is no utopia. Already 12 life-saving drugs, e.g....
Researchers identify key immune checkpoint protein that operates within T cells
Columbus, Ohio – A new study led by researchers at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Solove Research Institute (OSUCCC – James) has identified a protein within certain immune cells that is required for optimal immune responses to cancer. The findings, reported in the journal Science Advances,...
New weapon identified in arsenal against disease
Scientists at the Kennedy Institute of Rheumatology in the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences have discovered a new way for T cells to attack cells infected by viruses or deranged by cancer. Published online by the journal Science on Thursday 7 May 2020, the new research from the Dustin Group describes the...
Could cytotoxic T-cells be a key to longevity?
by RIKEN Scientists from the RIKEN Center for Integrative Medical Science (IMS) and Keio University School of Medicine in Japan have used single-cell RNA analysis to find that supercentenarians—meaning people over the age of 110—have an excess of a type of immune cell called cytotoxic CD4 T-cells. Supercentenarians are a unique group of people. First,...