IOS PRESS IMAGE: THE MODEL DIMENSIONS INCLUDE AMYLOIDOSIS (A), TAUOPATHY (T), PATHOPHYSIOLOGY (P), AND NEURODEGENERATION (N). THE DISEASE PROCESSES WITHIN THOSE DIMENSIONS PRODUCE A CLINICAL OUTPUT (O) INVOLVING VIGILANCE, SLEEP-WAKE CYCLE, COGNITIVE FUNCTIONS, AND ABILITIES IN THE ACTIVITIES OF DAILY LIVING. KEY: CSF, CEREBROSPINAL FLUID; PET, POSITRON EMISSION TOMOGRAPHY; EEG, ELECTROENCEPHALOGRAPHY; ERO, EVENT-RELATED EEG OSCILLATIONS;...
