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Exploring the effects of dasatinib, quercetin, and fisetin on DNA methylation clocks

by Impact Journals LLC Correlation between epigenetic clocks and immune cell types. The size of the dots is proportional to the correlation value, being blue a positive correlation and red a negative correlation. Credit: Aging (2024). DOI: 10.18632/aging.205581A new research paper titled “Exploring the effects of dasatinib, quercetin, and fisetin on DNA methylation clocks: a...

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Old weapon, new target: Dasatinib against angioimmunoblastic T-cell lymphoma

Researchers from the University of Tsukuba show that angioimmunoblastic T-cell lymphoma (AITL) is dependent on T-cell receptor (TCR) signaling and that dasatinib, a multi-kinase inhibitor that targets the TCR pathway, may improve treatment outcomes UNIVERSITY OF TSUKUBA Tsukuba, Japan – Angioimmunoblastic T-cell Lymphoma (AITL) is an intractable form of non-Hodgkin lymphoma with a bleak prognosis....