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Researchers reveal neural markers of sequential working memory deficits in de novo Parkinson’s disease
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Researchers reveal neural markers of sequential working memory deficits in de novo Parkinson’s disease

by Liu Jia,  Chinese Academy of Sciences Immunohistochemistry for alpha-synuclein showing positive staining (brown) of an intraneural Lewy-body in the Substantia nigra in Parkinson’s disease. A multi-institutional research team has demonstrated that hyper-activation and weakened functional connectivity of the subthalamic nucleus (STN) are neural markers of sequential working memory deficits in de novo Parkinson’s disease (PD). This study...